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| I | Santiago Wanderers | - | Santa Fe | 1:2 (0:2) | ||
| V | Santa Fe | - | Santiago Wanderers | 3:0 (1:0) | ||
| I: 14.02.2018 01:30 | V: 21.02.2018 01:30 | Campeones: Santa Fe | ||||
| I | Banfield | - | Nacional | 2:2 (0:0) | ||
| V | Nacional | - | Banfield | 1:0 (0:0) | ||
| I: 14.02.2018 23:00 | V: 22.02.2018 01:45 | Campeones: Nacional | ||||
| I | Vasco da Gama - RJ | - | Jorge Wilstermann | 4:0 (2:0) | ||
| V | Jorge Wilstermann | - | Vasco da Gama - RJ | 2:3 (3:0, 4:0) pn. | ||
| I: 15.02.2018 00:45 | V: 22.02.2018 01:45 | Campeones: Vasco da Gama - RJ | ||||
| I | Atlético Junior | - | Guaraní | 1:0 (0:0) | ||
| V | Guaraní | - | Atlético Junior | 0:0 (0:0) | ||
| I: 15.02.2018 23:15 | V: 23.02.2018 01:30 | Campeones: Atlético Junior | ||||
