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| 21.01.2018 | 12:00 | RB Linense | - | Lorca Deportiva | 2:0 (2:0) | |
| 12:00 | UD Melilla | - | FC Cartagena | 2:0 (2:0) | ||
| 12:00 | UCAM Murcia CF | - | FC Jumilla | 0:1 (0:1) | ||
| 12:00 | CF Villanovense | - | Las Palmas Atlético | 0:0 (0:0) | ||
| 12:00 | Marbella FC | - | Extremadura UD | 1:1 (0:1) | ||
| 16:00 | Córdoba B | - | San Fernando CD | 0:3 (0:2) | ||
| 17:00 | Écija Balompié | - | Betis B | 2:1 (1:1) | ||
| 17:00 | RC Recreativo | - | CD Badajoz | 2:0 (1:0) | ||
| 17:00 | CD El Ejido 2012 | - | Real Murcia | 0:2 (0:0) | ||
| 17:00 | Mérida AD | - | Granada B | 0:2 (0:1) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Cartagena | 22 | 12 | 6 | 4 | 31:22 | 9 | 42 |
| 2 |
|
Extremadura UD | 22 | 11 | 6 | 5 | 35:20 | 15 | 39 |
| 3 |
|
Marbella FC | 22 | 11 | 5 | 6 | 30:20 | 10 | 38 |
| 4 |
|
Real Murcia | 22 | 10 | 7 | 5 | 29:18 | 11 | 37 |
| 5 |
|
UCAM Murcia CF | 22 | 10 | 6 | 6 | 22:20 | 2 | 36 |
| 6 |
|
Granada B | 22 | 9 | 7 | 6 | 23:18 | 5 | 34 |
| 7 |
|
UD Melilla | 22 | 10 | 4 | 8 | 21:13 | 8 | 34 |
| 8 |
|
RB Linense | 22 | 8 | 7 | 7 | 30:22 | 8 | 31 |
| 9 |
|
San Fernando CD | 22 | 8 | 6 | 8 | 29:26 | 3 | 30 |
| 10 |
|
CD El Ejido 2012 | 22 | 7 | 8 | 7 | 33:32 | 1 | 29 |
| 11 |
|
RC Recreativo | 22 | 7 | 8 | 7 | 21:19 | 2 | 29 |
| 12 |
|
Écija Balompié | 22 | 7 | 7 | 8 | 24:32 | -8 | 28 |
| 13 |
|
CF Villanovense | 22 | 6 | 9 | 7 | 16:22 | -6 | 27 |
| 14 |
|
CD Badajoz | 22 | 6 | 8 | 8 | 28:28 | 0 | 26 |
| 15 |
|
Mérida AD | 22 | 6 | 8 | 8 | 21:24 | -3 | 26 |
| 16 |
|
Córdoba B | 22 | 5 | 8 | 9 | 28:32 | -4 | 23 |
| 17 |
|
FC Jumilla | 22 | 5 | 8 | 9 | 18:29 | -11 | 23 |
| 18 |
|
Betis B | 22 | 5 | 7 | 10 | 26:38 | -12 | 22 |
| 19 |
|
Las Palmas Atlético | 22 | 5 | 5 | 12 | 24:32 | -8 | 20 |
| 20 |
|
Lorca Deportiva | 22 | 4 | 6 | 12 | 20:42 | -22 | 18 |
| Playoff | |
| Playoff | |
| Permanencia | |
| Descenso |
