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| 31.07.2021 | 19:00 | Villa Dálmine | - | Atlético Rafaela | 1:0 (0:0) | |
| 20:00 | Defensores de Belgrano | - | Barracas Central | 0:0 (0:0) | ||
| 20:30 | All Boys | - | Brown de Adrogué | 1:1 (0:0) | ||
| 21:00 | San Martín de San Juan | - | Guillermo Brown | 0:0 (0:0) | ||
| 01.08.2021 | 20:00 | Almagro | - | Gimnasia de Jujuy | 2:2 (1:1) | |
| 20:00 | Güemes de SdE | - | Tristan Suárez | 0:0 (0:0) | ||
| 20:00 | Deportivo Morón | - | Ferro Carril Oeste | 1:0 (1:0) | ||
| 20:00 | San Telmo | - | Independiente Rivadavia | 1:0 (1:0) | ||
| 02.08.2021 | 20:00 | Ramón Santamarina | - | Instituto de Córdoba | 0:0 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Güemes de SdE | 19 | 9 | 8 | 2 | 23:14 | 9 | 35 |
| 2 |
|
Barracas Central | 19 | 8 | 8 | 3 | 23:19 | 4 | 32 |
| 3 |
|
Deportivo Morón | 19 | 9 | 3 | 7 | 22:20 | 2 | 30 |
| 4 |
|
Brown de Adrogué | 19 | 7 | 7 | 5 | 20:16 | 4 | 28 |
|
Defensores de Belgrano | 19 | 6 | 10 | 3 | 20:16 | 4 | 28 | |
| 6 |
|
Gimnasia de Jujuy | 19 | 7 | 7 | 5 | 19:16 | 3 | 28 |
| 7 |
|
Almagro | 19 | 8 | 4 | 7 | 24:25 | -1 | 28 |
| 8 |
|
Independiente Rivadavia | 19 | 5 | 10 | 4 | 23:21 | 2 | 25 |
| 9 |
|
Tristan Suárez | 19 | 6 | 6 | 7 | 28:25 | 3 | 24 |
| 10 |
|
Atlético Rafaela | 19 | 6 | 6 | 7 | 20:18 | 2 | 24 |
| 11 |
|
Ferro Carril Oeste | 19 | 6 | 6 | 7 | 17:20 | -3 | 24 |
| 12 |
|
Instituto de Córdoba | 19 | 4 | 11 | 4 | 17:19 | -2 | 23 |
| 13 |
|
San Telmo | 19 | 5 | 8 | 6 | 18:24 | -6 | 23 |
| 14 |
|
All Boys | 19 | 5 | 7 | 7 | 17:19 | -2 | 22 |
| 15 |
|
San Martín de San Juan | 19 | 4 | 8 | 7 | 24:25 | -1 | 20 |
| 16 |
|
Ramón Santamarina | 19 | 4 | 8 | 7 | 16:19 | -3 | 20 |
| 17 |
|
Villa Dálmine | 19 | 2 | 10 | 7 | 8:14 | -6 | 16 |
| 18 |
|
Guillermo Brown | 19 | 2 | 9 | 8 | 12:21 | -9 | 15 |
| Próxima ronda | |
| Playoff |
