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| 04.03.2022 | 21:30 | Brown de Adrogué | - | Deportivo Morón | 1:0 (0:0) | |
| 05.03.2022 | 01:00 | Tristan Suárez | - | Alvarado | 3:3 (1:0) | |
| 01:10 | San Martín de Tucumán | - | Estudiantes de Río Cuarto | 2:0 (2:0) | ||
| 21:00 | Atlanta | - | Belgrano | 1:1 (1:0) | ||
| 21:00 | Defensores de Belgrano | - | Deportivo Madryn | 1:2 (0:1) | ||
| 22:00 | Agropecuario Argentino | - | Almagro | 2:2 (1:1) | ||
| 23:30 | Instituto de Córdoba | - | Nueva Chicago | 2:1 (2:0) | ||
| 06.03.2022 | 01:30 | Estudiantes de Caseros | - | Villa Dálmine | 2:2 (2:2) | |
| 21:00 | Chacarita Juniors | - | Temperley | 2:2 (1:1) | ||
| 21:00 | Guillermo Brown | - | Flandria | 1:0 (1:0) | ||
| 21:00 | Sacachispas | - | Deportivo Maipú | 1:1 (0:0) | ||
| 21:30 | San Martín de San Juan | - | Deportivo Riestra | 0:1 (0:0) | ||
| 23:00 | Atlético Rafaela | - | Gimnasia de Jujuy | 3:0 (0:0) | ||
| 23:30 | Chaco For Ever | - | Güemes de SdE | 0:0 (0:0) | ||
| 07.03.2022 | 01:00 | Mitre de SdE | - | Quilmes | 1:3 (1:1) | |
| 21:00 | San Telmo | - | All Boys | 1:1 (0:1) | ||
| 23:15 | Ramón Santamarina | - | Almirante Brown | 2:2 (1:1) | ||
| 08.03.2022 | 01:10 | Ferro Carril Oeste | - | Independiente Rivadavia | 0:0 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Brown de Adrogué | 4 | 3 | 1 | 0 | 8:3 | 5 | 10 |
| 2 |
|
San Martín de Tucumán | 4 | 3 | 1 | 0 | 6:2 | 4 | 10 |
| 3 |
|
Deportivo Riestra | 4 | 3 | 1 | 0 | 4:0 | 4 | 10 |
| 4 |
|
Belgrano | 4 | 3 | 1 | 0 | 5:2 | 3 | 10 |
| 5 |
|
Guillermo Brown | 4 | 3 | 0 | 1 | 7:5 | 2 | 9 |
| 6 |
|
All Boys | 4 | 2 | 2 | 0 | 5:3 | 2 | 8 |
| 7 |
|
Deportivo Maipú | 4 | 2 | 2 | 0 | 4:2 | 2 | 8 |
|
Instituto de Córdoba | 4 | 2 | 2 | 0 | 4:2 | 2 | 8 | |
| 9 |
|
Almirante Brown | 4 | 2 | 1 | 1 | 8:7 | 1 | 7 |
| 10 |
|
Almagro | 4 | 2 | 1 | 1 | 5:4 | 1 | 7 |
|
Deportivo Madryn | 4 | 2 | 1 | 1 | 5:4 | 1 | 7 | |
| 12 |
|
Quilmes | 3 | 2 | 0 | 1 | 5:3 | 2 | 6 |
| 13 |
|
Chaco For Ever | 4 | 1 | 3 | 0 | 4:3 | 1 | 6 |
| 14 |
|
Independiente Rivadavia | 3 | 1 | 2 | 0 | 2:1 | 1 | 5 |
| 15 |
|
Chacarita Juniors | 4 | 1 | 2 | 1 | 6:7 | -1 | 5 |
|
Gimnasia de Jujuy | 4 | 1 | 2 | 1 | 6:7 | -1 | 5 | |
| 17 |
|
Estudiantes de Río Cuarto | 4 | 1 | 2 | 1 | 3:4 | -1 | 5 |
| 18 |
|
Atlético Rafaela | 4 | 1 | 1 | 2 | 4:3 | 1 | 4 |
| 19 |
|
Ramón Santamarina | 4 | 1 | 1 | 2 | 5:5 | 0 | 4 |
|
Temperley | 4 | 1 | 1 | 2 | 5:5 | 0 | 4 | |
|
Tristan Suárez | 4 | 0 | 4 | 0 | 5:5 | 0 | 4 | |
| 22 |
|
Alvarado | 4 | 0 | 4 | 0 | 4:4 | 0 | 4 |
|
Atlanta | 4 | 1 | 1 | 2 | 4:4 | 0 | 4 | |
| 24 |
|
Ferro Carril Oeste | 4 | 1 | 1 | 2 | 2:3 | -1 | 4 |
|
San Martín de San Juan | 4 | 1 | 1 | 2 | 2:3 | -1 | 4 | |
| 26 |
|
Gimnasia de Mendoza | 3 | 1 | 0 | 2 | 3:2 | 1 | 3 |
| 27 |
|
Estudiantes de Caseros | 4 | 0 | 3 | 1 | 4:5 | -1 | 3 |
| 28 |
|
Sacachispas | 4 | 0 | 3 | 1 | 3:4 | -1 | 3 |
| 29 |
|
Deportivo Morón | 4 | 0 | 3 | 1 | 1:2 | -1 | 3 |
| 30 |
|
Güemes de SdE | 4 | 0 | 3 | 1 | 3:5 | -2 | 3 |
| 31 |
|
Agropecuario Argentino | 4 | 0 | 2 | 2 | 2:4 | -2 | 2 |
|
Nueva Chicago | 4 | 0 | 2 | 2 | 2:4 | -2 | 2 | |
| 33 |
|
Defensores de Belgrano | 4 | 0 | 2 | 2 | 3:6 | -3 | 2 |
| 34 |
|
San Telmo | 3 | 0 | 2 | 1 | 2:5 | -3 | 2 |
| 35 |
|
Villa Dálmine | 4 | 0 | 2 | 2 | 4:8 | -4 | 2 |
| 36 |
|
Mitre de SdE | 4 | 0 | 1 | 3 | 2:6 | -4 | 1 |
| 37 |
|
Flandria | 4 | 0 | 1 | 3 | 2:7 | -5 | 1 |
| Ascenso | |
| Playoff | |
| Playoff | |
| Descenso |
