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| 30.04.2021 | 23:00 | Vélez Sarsfield | - | Patronato de Paraná | 1:0 (1:0) | |
| 01.05.2021 | 02:00 | Colón de Santa Fe | - | Arsenal de Sarandí | 2:0 (2:0) | |
| 02.05.2021 | 15:00 | Boca Juniors | - | CA Lanús | 1:0 (0:0) | |
| 17:10 | Independiente | - | Atlético Tucumán | 0:1 (0:1) | ||
| 17:10 | Defensa y Justicia | - | Unión de Santa Fe | 0:1 (0:0) | ||
| 19:20 | San Lorenzo | - | Godoy Cruz | 1:0 (1:0) | ||
| 19:20 | Talleres de Córdoba | - | Huracán | 1:1 (1:0) | ||
| 21:30 | Banfield | - | River Plate | 1:0 (0:0) | ||
| 23:40 | Aldosivi | - | Argentinos Juniors | 1:3 (1:1) | ||
| 23:40 | Central Córdoba SdE | - | Racing Club | 1:0 (0:0) | ||
| 03.05.2021 | 02:00 | Rosario Central | - | Newell's Old Boys | 3:0 (1:0) | |
| 20:45 | Sarmiento de Junín | - | Gimnasia de La Plata | 0:0 (0:0) | ||
| 23:00 | Estudiantes | - | Platense | 2:0 (2:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta | 1.ª parte | 2.ª parte |
| 1 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Colón de Santa Fe | 12 | 7 | 3 | 2 | 22:9 | 13 | 24 |
| 2 |
|
Estudiantes | 12 | 6 | 4 | 2 | 16:8 | 8 | 22 |
| 3 |
|
San Lorenzo | 12 | 6 | 3 | 3 | 16:14 | 2 | 21 |
| 4 |
|
River Plate | 12 | 5 | 3 | 4 | 21:10 | 11 | 18 |
| 5 |
|
Rosario Central | 12 | 5 | 3 | 4 | 15:14 | 1 | 18 |
| 6 |
|
Racing Club | 12 | 5 | 3 | 4 | 12:12 | 0 | 18 |
| 7 |
|
Banfield | 12 | 4 | 5 | 3 | 13:12 | 1 | 17 |
| 8 |
|
Argentinos Juniors | 12 | 4 | 4 | 4 | 12:11 | 1 | 16 |
| 9 |
|
Central Córdoba SdE | 12 | 4 | 4 | 4 | 13:16 | -3 | 16 |
| 10 |
|
Godoy Cruz | 12 | 4 | 3 | 5 | 18:23 | -5 | 15 |
| 11 |
|
Aldosivi | 12 | 3 | 2 | 7 | 14:17 | -3 | 11 |
| 12 |
|
Platense | 12 | 3 | 2 | 7 | 8:18 | -10 | 11 |
| 13 |
|
Arsenal de Sarandí | 12 | 3 | 2 | 7 | 10:22 | -12 | 11 |
| 2 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Vélez Sarsfield | 12 | 9 | 1 | 2 | 18:13 | 5 | 28 |
| 2 |
|
Boca Juniors | 12 | 6 | 4 | 2 | 22:11 | 11 | 22 |
| 3 |
|
Talleres de Córdoba | 12 | 5 | 5 | 2 | 19:15 | 4 | 20 |
| 4 |
|
Unión de Santa Fe | 12 | 4 | 6 | 2 | 11:13 | -2 | 18 |
| 5 |
|
Independiente | 12 | 5 | 2 | 5 | 13:9 | 4 | 17 |
| 6 |
|
CA Lanús | 12 | 5 | 1 | 6 | 17:18 | -1 | 16 |
| 7 |
|
Gimnasia de La Plata | 12 | 3 | 6 | 3 | 15:15 | 0 | 15 |
| 8 |
|
Atlético Tucumán | 12 | 4 | 3 | 5 | 19:20 | -1 | 15 |
| 9 |
|
Huracán | 12 | 2 | 7 | 3 | 13:14 | -1 | 13 |
| 10 |
|
Defensa y Justicia | 12 | 3 | 3 | 6 | 15:16 | -1 | 12 |
| 11 |
|
Sarmiento de Junín | 12 | 2 | 5 | 5 | 9:18 | -9 | 11 |
| 12 |
|
Newell's Old Boys | 12 | 2 | 4 | 6 | 13:20 | -7 | 10 |
| 13 |
|
Patronato de Paraná | 12 | 3 | 0 | 9 | 11:17 | -6 | 9 |
| Playoff | |
| Playoff |
