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| 05.05.2018 | 01:00 | Unión Española | - | San Luis | 4:0 (2:0) | |
| 17:00 | Deportes Iquique | - | Curicó Unido | 2:2 (1:0) | ||
| 20:00 | Antofagasta | - | Deportes Temuco | 3:2 (2:0) | ||
| 22:30 | Unión La Calera | - | Audax Italiano | 1:0 (0:0) | ||
| 06.05.2018 | 01:00 | Universidad Católica | - | Huachipato | 3:1 (1:1) | |
| 17:00 | O'Higgins | - | Universidad de Chile | 0:1 (0:1) | ||
| 20:00 | Palestino | - | Universidad de Concepción | 1:2 (0:0) | ||
| 22:30 | Colo-Colo | - | Everton | 3:1 (1:1) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Universidad Católica | 12 | 10 | 1 | 1 | 19:7 | 12 | 31 |
| 2 |
|
Universidad de Concepción | 12 | 8 | 2 | 2 | 19:13 | 6 | 26 |
| 3 |
|
Universidad de Chile | 12 | 8 | 0 | 4 | 19:17 | 2 | 24 |
| 4 |
|
Colo-Colo | 12 | 7 | 2 | 3 | 19:12 | 7 | 23 |
| 5 |
|
Unión La Calera | 12 | 7 | 1 | 4 | 18:12 | 6 | 22 |
| 6 |
|
Antofagasta | 12 | 6 | 4 | 2 | 19:15 | 4 | 22 |
| 7 |
|
Unión Española | 12 | 5 | 4 | 3 | 22:17 | 5 | 19 |
| 8 |
|
O'Higgins | 12 | 5 | 2 | 5 | 19:15 | 4 | 17 |
| 9 |
|
Huachipato | 12 | 4 | 4 | 4 | 18:14 | 4 | 16 |
| 10 |
|
Deportes Iquique | 12 | 3 | 3 | 6 | 16:17 | -1 | 12 |
| 11 |
|
Palestino | 12 | 3 | 3 | 6 | 17:20 | -3 | 12 |
| 12 |
|
Curicó Unido | 12 | 1 | 7 | 4 | 17:19 | -2 | 10 |
| 13 |
|
San Luis | 12 | 2 | 4 | 6 | 6:18 | -12 | 10 |
| 14 |
|
Audax Italiano | 12 | 1 | 4 | 7 | 10:19 | -9 | 7 |
| 15 |
|
Everton | 12 | 2 | 1 | 9 | 10:21 | -11 | 7 |
| 16 |
|
Deportes Temuco | 12 | 1 | 4 | 7 | 9:21 | -12 | 7 |
| Copa Libertadores | |
| Copa Sudamericana | |
| Descenso |
