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| I | Sporting CP | - | İstanbul Başakşehir | 3:1 (2:0) | ||
| V | İstanbul Başakşehir | - | Sporting CP | 4:1 (2:0, 3:1) pró. | ||
| I: 20.02.2020 18:55 | V: 27.02.2020 18:55 | Campeones: İstanbul Başakşehir | ||||
| I | Getafe | - | AFC Ajax | 2:0 (1:0) | ||
| V | AFC Ajax | - | Getafe | 2:1 (1:1) | ||
| I: 20.02.2020 18:55 | V: 27.02.2020 21:00 | Campeones: Getafe | ||||
| I | FC København | - | Celtic FC | 1:1 (0:1) | ||
| V | Celtic FC | - | FC København | 1:3 (0:0) | ||
| I: 20.02.2020 18:55 | V: 27.02.2020 21:00 | Campeones: FC København | ||||
| I | CFR Cluj | - | Sevilla | 1:1 (0:0) | ||
| V | Sevilla | - | CFR Cluj | 0:0 (0:0) | ||
| I: 20.02.2020 18:55 | V: 27.02.2020 21:00 | Campeones: Sevilla | ||||
| I | Club Brugge KV | - | Manchester United | 1:1 (1:1) | ||
| V | Manchester United | - | Club Brugge KV | 5:0 (3:0) | ||
| I: 20.02.2020 18:55 | V: 27.02.2020 21:00 | Campeones: Manchester United | ||||
| I | PFC Ludogorets Razgrad | - | Inter | 0:2 (0:0) | ||
| V | Inter | - | PFC Ludogorets Razgrad | 2:1 (2:1) | ||
| I: 20.02.2020 18:55 | V: 27.02.2020 21:00 | Campeones: Inter | ||||
| I | Eintracht Frankfurt | - | RB Salzburg | 4:1 (2:0) | ||
| V | RB Salzburg | - | Eintracht Frankfurt | 2:2 (1:1) | ||
| I: 20.02.2020 18:55 | V: 28.02.2020 18:00 | Campeones: Eintracht Frankfurt | ||||
| I | Shakhtar Donetsk | - | Benfica | 2:1 (0:0) | ||
| V | Benfica | - | Shakhtar Donetsk | 3:3 (2:1) | ||
| I: 20.02.2020 18:55 | V: 27.02.2020 21:00 | Campeones: Shakhtar Donetsk | ||||
| I | Wolverhampton Wanderers | - | Espanyol | 4:0 (1:0) | ||
| V | Espanyol | - | Wolverhampton Wanderers | 3:2 (1:1) | ||
| I: 20.02.2020 21:00 | V: 27.02.2020 18:55 | Campeones: Wolverhampton Wanderers | ||||
| I | Bayer Leverkusen | - | Oporto | 2:1 (1:0) | ||
| V | Oporto | - | Bayer Leverkusen | 1:3 (0:1) | ||
| I: 20.02.2020 21:00 | V: 27.02.2020 18:55 | Campeones: Bayer Leverkusen | ||||
| I | APOEL Nikosia | - | Basilea | 0:3 (0:1) | ||
| V | Basilea | - | APOEL Nikosia | 1:0 (1:0) | ||
| I: 20.02.2020 21:00 | V: 27.02.2020 18:55 | Campeones: Basilea | ||||
| I | Olympiacos | - | Arsenal | 0:1 (0:0) | ||
| V | Arsenal | - | Olympiacos | 1:2 (0:0, 0:1) pró. | ||
| I: 20.02.2020 21:00 | V: 27.02.2020 21:00 | Campeones: Olympiacos | ||||
| I | AZ Alkmaar | - | LASK | 1:1 (0:1) | ||
| V | LASK | - | AZ Alkmaar | 2:0 (1:0) | ||
| I: 20.02.2020 21:00 | V: 27.02.2020 18:55 | Campeones: LASK | ||||
| I | Wolfsburgo | - | Malmoe | 2:1 (0:0) | ||
| V | Malmoe | - | Wolfsburgo | 0:3 (0:1) | ||
| I: 20.02.2020 21:00 | V: 27.02.2020 18:55 | Campeones: Wolfsburgo | ||||
| I | Roma | - | Gante | 1:0 (1:0) | ||
| V | Gante | - | Roma | 1:1 (1:1) | ||
| I: 20.02.2020 21:00 | V: 27.02.2020 18:55 | Campeones: Roma | ||||
| I | Rangers FC | - | Sporting Braga | 3:2 (0:1) | ||
| V | Sporting Braga | - | Rangers FC | 0:1 (0:0) | ||
| I: 20.02.2020 21:00 | V: 26.02.2020 18:00 | Campeones: Rangers FC | ||||
