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| I | Granada | - | Manchester United | 0:2 (0:1) | ||
| V | Manchester United | - | Granada | 2:0 (1:0) | ||
| I: 08.04.2021 21:00 | V: 15.04.2021 21:00 | Campeones: Manchester United | ||||
| I | Arsenal | - | Slavia Praga | 1:1 (0:0) | ||
| V | Slavia Praga | - | Arsenal | 0:4 (0:3) | ||
| I: 08.04.2021 21:00 | V: 15.04.2021 21:00 | Campeones: Arsenal | ||||
| I | AFC Ajax | - | Roma | 1:2 (1:0) | ||
| V | Roma | - | AFC Ajax | 1:1 (0:0) | ||
| I: 08.04.2021 21:00 | V: 15.04.2021 21:00 | Campeones: Roma | ||||
| I | Dinamo Zagreb | - | Villarreal | 0:1 (0:1) | ||
| V | Villarreal | - | Dinamo Zagreb | 2:1 (2:0) | ||
| I: 08.04.2021 21:00 | V: 15.04.2021 21:00 | Campeones: Villarreal | ||||
