 |
 |
|
| I | Neftçi PFK | - | HJK Helsinki | 2:2 (0:0) | ||
| V | HJK Helsinki | - | Neftçi PFK | 3:0 (0:0) | ||
| I: 03.08.2021 19:00 | V: 12.08.2021 18:00 | Campeones: HJK Helsinki | ||||
| I | FK Kairat | - | FC Alashkert | 0:0 (0:0) | ||
| V | FC Alashkert | - | FK Kairat | 3:2 (1:1, 2:2) pró. | ||
| I: 05.08.2021 16:00 | V: 12.08.2021 17:00 | Campeones: FC Alashkert | ||||
| I | FK Jablonec | - | Celtic FC | 2:4 (1:2) | ||
| V | Celtic FC | - | FK Jablonec | 3:0 (1:0) | ||
| I: 05.08.2021 17:45 | V: 12.08.2021 20:45 | Campeones: Celtic FC | ||||
| I | Omonia Nikosia | - | FC Flora | 1:0 (1:0) | ||
| V | FC Flora | - | Omonia Nikosia | 4:5 (0:1, 2:1, 2:1) pn. | ||
| I: 05.08.2021 18:00 | V: 10.08.2021 18:00 | Campeones: Omonia Nikosia | ||||
| I | Lincoln Red Imps | - | Slovan Bratislava | 1:3 (0:1) | ||
| V | Slovan Bratislava | - | Lincoln Red Imps | 1:1 (1:0) | ||
| I: 05.08.2021 18:00 | V: 10.08.2021 20:30 | Campeones: Slovan Bratislava | ||||
| I | NŠ Mura | - | FK Žalgiris | 0:0 (0:0) | ||
| V | FK Žalgiris | - | NŠ Mura | 0:1 (0:1) | ||
| I: 05.08.2021 20:00 | V: 12.08.2021 19:00 | Campeones: NŠ Mura | ||||
| I | Galatasaray | - | St. Johnstone FC | 1:1 (0:0) | ||
| V | St. Johnstone FC | - | Galatasaray | 2:4 (1:1) | ||
| I: 05.08.2021 20:00 | V: 12.08.2021 20:00 | Campeones: Galatasaray | ||||
| I | Rapid Wien | - | Anorthosis Famagusta | 3:0 (1:0) | ||
| V | Anorthosis Famagusta | - | Rapid Wien | 2:1 (1:0) | ||
| I: 05.08.2021 20:30 | V: 12.08.2021 19:00 | Campeones: Rapid Wien | ||||
