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| I | PAS Giannina | - | Panionios GSS | 1:1 (1:1) | ||
| V | Panionios GSS | - | PAS Giannina | 2:0 (0:0) | ||
| I: 08.01.2019 14:00 | V: 22.01.2019 14:00 | Campeones: Panionios GSS | ||||
| I | Panachaiki GE | - | PAOK Saloniki | 2:1 (1:0) | ||
| V | PAOK Saloniki | - | Panachaiki GE | 5:0 (2:0) | ||
| I: 08.01.2019 16:00 | V: 22.01.2019 18:30 | Campeones: PAOK Saloniki | ||||
| I | Xanthi FC | - | Olympiacos | 0:0 (0:0) | ||
| V | Olympiacos | - | Xanthi FC | 3:1 (1:0) | ||
| I: 08.01.2019 16:15 | V: 23.01.2019 18:30 | Campeones: Olympiacos | ||||
| I | Ergotelis | - | OFI Heraklion | 1:1 (0:1) | ||
| V | OFI Heraklion | - | Ergotelis | 3:4 (1:1, 1:1, 1:1) pn. | ||
| I: 08.01.2019 18:30 | V: 24.01.2019 16:15 | Campeones: Ergotelis | ||||
| I | Apollon Smyrnis | - | Atromitos | 0:3 (0:1) | ||
| V | Atromitos | - | Apollon Smyrnis | 2:1 (1:0) | ||
| I: 09.01.2019 14:00 | V: 23.01.2019 14:00 | Campeones: Atromitos | ||||
| I | AE Lárissa | - | Asteras Tripolis | 3:2 (3:1) | ||
| V | Asteras Tripolis | - | AE Lárissa | 5:3 (2:0) | ||
| I: 09.01.2019 16:15 | V: 23.01.2019 16:15 | Campeones: Asteras Tripolis | ||||
| I | Chania Kissamikos | - | AEK Athen | 1:1 (0:1) | ||
| V | AEK Athen | - | Chania Kissamikos | 5:0 (2:0) | ||
| I: 09.01.2019 18:30 | V: 23.01.2019 16:15 | Campeones: AEK Athen | ||||
| I | Lamia | - | Panathinaikos | 1:0 (0:0) | ||
| V | Panathinaikos | - | Lamia | 2:4 (0:0, 1:0, 1:0) pn. | ||
| I: 10.01.2019 18:30 | V: 24.01.2019 18:30 | Campeones: Lamia | ||||
