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| I | AEK Athen | - | Volos NFC | 4:2 (4:1) | ||
| V | Volos NFC | - | AEK Athen | 1:0 (1:0) | ||
| I: 10.02.2021 16:00 | V: 04.03.2021 17:00 | Campeones: AEK Athen | ||||
| I | PAOK Saloniki | - | Lamia | 5:2 (2:2) | ||
| V | Lamia | - | PAOK Saloniki | 1:1 (0:1) | ||
| I: 10.02.2021 18:00 | V: 03.03.2021 17:00 | Campeones: PAOK Saloniki | ||||
| I | Olympiacos | - | Aris Saloniki | 2:1 (2:1) | ||
| V | Aris Saloniki | - | Olympiacos | 1:1 (0:0) | ||
| I: 10.02.2021 20:30 | V: 04.03.2021 19:00 | Campeones: Olympiacos | ||||
| I | PAS Giannina | - | Panathinaikos | 2:1 (1:1) | ||
| V | Panathinaikos | - | PAS Giannina | 1:2 (0:2) | ||
| I: 18.02.2021 14:00 | V: 03.03.2021 19:00 | Campeones: PAS Giannina | ||||
