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| 04.01.2011 | 16:15 | Atromitos | - | AE Lárissa | 3:0 (2:0) | |
| 16:15 | Skoda Xanthi | - | Panathinaikos | 0:2 (0:1) | ||
| 18:30 | Aris Saloniki | - | AO Kavala | 1:0 (1:0) | ||
| 05.01.2011 | 14:00 | Asteras Tripolis | - | Ergotelis | 3:0 (1:0) | |
| 16:15 | Olympiacos Volou | - | Panionios GSS | 0:0 (0:0) | ||
| 16:15 | AEK Athen | - | AO Kerkyra | 0:0 (0:0) | ||
| 18:30 | Olympiacos | - | Iraklis Saloniki | 2:0 (1:0) | ||
| 18:30 | Panserraikos | - | PAOK Saloniki | 1:1 (0:1) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Olympiacos | 16 | 13 | 0 | 3 | 31:7 | 24 | 39 |
| 2 |
|
Panathinaikos | 16 | 10 | 4 | 2 | 25:11 | 14 | 34 |
| 3 |
|
AEK Athen | 16 | 7 | 3 | 6 | 23:16 | 7 | 24 |
| 4 |
|
PAOK Saloniki | 16 | 7 | 3 | 6 | 17:17 | 0 | 24 |
| 5 |
|
Aris Saloniki | 16 | 7 | 2 | 7 | 11:13 | -2 | 23 |
| 6 |
|
Olympiacos Volou | 16 | 4 | 9 | 3 | 16:15 | 1 | 21 |
| 7 |
|
AO Kavala | 16 | 5 | 6 | 5 | 15:14 | 1 | 21 |
| 8 |
|
Skoda Xanthi | 16 | 5 | 6 | 5 | 15:18 | -3 | 21 |
| 9 |
|
AO Kerkyra | 16 | 5 | 5 | 6 | 14:18 | -4 | 20 |
| 10 |
|
Ergotelis | 16 | 6 | 2 | 8 | 16:22 | -6 | 20 |
| 11 |
|
Atromitos | 16 | 4 | 7 | 5 | 17:18 | -1 | 19 |
| 12 |
|
Asteras Tripolis | 16 | 4 | 7 | 5 | 13:14 | -1 | 19 |
| 13 |
|
Iraklis Saloniki | 16 | 4 | 7 | 5 | 13:15 | -2 | 19 |
| 14 |
|
Panserraikos | 16 | 4 | 4 | 8 | 13:21 | -8 | 16 |
| 15 |
|
Panionios GSS | 16 | 4 | 4 | 8 | 9:18 | -9 | 16 |
| 16 |
|
AE Lárissa | 16 | 2 | 5 | 9 | 10:21 | -11 | 11 |
| Champions League | |
| Playoff | |
| Descenso |
