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| 02.10.2010 | 16:15 | Asteras Tripolis | - | Atromitos | 1:1 (1:0) | |
| 16:15 | Olympiacos | - | Olympiacos Volou | 3:1 (2:0) | ||
| 18:30 | AO Kavala | - | Panionios GSS | 2:1 (1:0) | ||
| 03.10.2010 | 15:00 | AO Kerkyra | - | Iraklis Saloniki | 0:0 (0:0) | |
| 17:15 | Ergotelis | - | Panathinaikos | 1:4 (0:3) | ||
| 17:15 | Panserraikos | - | AE Lárissa | 1:0 (1:0) | ||
| 17:15 | AEK Athen | - | Skoda Xanthi | 1:0 (1:0) | ||
| 19:30 | PAOK Saloniki | - | Aris Saloniki | 0:1 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Olympiacos | 5 | 4 | 0 | 1 | 10:3 | 7 | 12 |
| 2 |
|
Panathinaikos | 5 | 3 | 2 | 0 | 10:5 | 5 | 11 |
| 3 |
|
Aris Saloniki | 5 | 3 | 0 | 2 | 3:2 | 1 | 9 |
| 4 |
|
AO Kerkyra | 5 | 2 | 2 | 1 | 6:5 | 1 | 8 |
| 5 |
|
AO Kavala | 5 | 2 | 2 | 1 | 5:4 | 1 | 8 |
| 6 |
|
Iraklis Saloniki | 5 | 2 | 2 | 1 | 4:3 | 1 | 8 |
| 7 |
|
AEK Athen | 5 | 2 | 1 | 2 | 7:7 | 0 | 7 |
| 8 |
|
Olympiacos Volou | 5 | 2 | 1 | 2 | 6:6 | 0 | 7 |
| 9 |
|
Asteras Tripolis | 5 | 1 | 3 | 1 | 4:6 | -2 | 6 |
| 10 |
|
Ergotelis | 5 | 2 | 0 | 3 | 3:6 | -3 | 6 |
| 11 |
|
PAOK Saloniki | 5 | 1 | 2 | 2 | 4:5 | -1 | 5 |
| 12 |
|
Skoda Xanthi | 5 | 1 | 2 | 2 | 3:4 | -1 | 5 |
| 13 |
|
AE Lárissa | 5 | 1 | 2 | 2 | 2:3 | -1 | 5 |
| 14 |
|
Atromitos | 5 | 1 | 2 | 2 | 5:7 | -2 | 5 |
| 15 |
|
Panionios GSS | 5 | 1 | 1 | 3 | 4:6 | -2 | 4 |
| 16 |
|
Panserraikos | 5 | 1 | 0 | 4 | 4:8 | -4 | 3 |
| Champions League | |
| Playoff | |
| Descenso |
