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| 20.02.2022 | 14:30 | Calcio Lecco 1912 | - | Mantova 1911 SSD | 2:0 (1:0) | |
| 14:30 | FC Legnago Salus | - | FeralpiSalò | 0:3 (0:0) | ||
| 14:30 | Pro Vercelli | - | AC Renate | 1:1 (1:1) | ||
| 14:30 | FC Südtirol | - | Aurora Pro Patria | 0:0 (0:0) | ||
| 14:30 | Seregno | - | Juventus II | 2:2 (2:0) | ||
| 14:30 | AC Pro Sesto | - | Piacenza Calcio | 2:1 (1:1) | ||
| 14:30 | Trento Calcio 1921 | - | Calcio Padova | 2:2 (1:2) | ||
| 14:30 | UC AlbinoLeffe | - | US Pergolettese | 1:1 (1:1) | ||
| 14:30 | US Fiorenzuola | - | US Triestina | 0:1 (0:1) | ||
| 14:30 | Virtus Verona | - | Giana Erminio | 1:1 (1:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Südtirol | 28 | 21 | 7 | 0 | 37:6 | 31 | 70 |
| 2 |
|
Calcio Padova | 28 | 17 | 9 | 2 | 46:20 | 26 | 60 |
| 3 |
|
FeralpiSalò | 28 | 15 | 7 | 6 | 45:23 | 22 | 52 |
| 4 |
|
AC Renate | 28 | 15 | 6 | 7 | 46:29 | 17 | 51 |
| 5 |
|
US Triestina | 28 | 12 | 8 | 8 | 31:27 | 4 | 44 |
| 6 |
|
Juventus II | 28 | 12 | 6 | 10 | 32:31 | 1 | 42 |
| 7 |
|
Calcio Lecco 1912 | 28 | 12 | 5 | 11 | 37:30 | 7 | 41 |
| 8 |
|
Pro Vercelli | 28 | 10 | 10 | 8 | 29:28 | 1 | 40 |
| 9 |
|
Piacenza Calcio | 28 | 8 | 11 | 9 | 33:36 | -3 | 35 |
| 10 |
|
Mantova 1911 SSD | 28 | 7 | 13 | 8 | 27:28 | -1 | 34 |
| 11 |
|
UC AlbinoLeffe | 28 | 7 | 12 | 9 | 29:30 | -1 | 33 |
| 12 |
|
Trento Calcio 1921 | 28 | 7 | 10 | 11 | 23:28 | -5 | 31 |
| 13 |
|
AC Pro Sesto | 28 | 6 | 11 | 11 | 25:34 | -9 | 29 |
| 14 |
|
Virtus Verona | 28 | 5 | 14 | 9 | 24:29 | -5 | 29 |
| 15 |
|
US Pergolettese | 28 | 7 | 8 | 13 | 31:47 | -16 | 28 |
| 16 |
|
Aurora Pro Patria | 28 | 5 | 13 | 10 | 22:35 | -13 | 28 |
| 17 |
|
US Fiorenzuola | 28 | 6 | 9 | 13 | 24:35 | -11 | 27 |
| 18 |
|
Seregno | 28 | 6 | 8 | 14 | 31:40 | -9 | 26 |
| 19 |
|
Giana Erminio | 28 | 4 | 12 | 12 | 17:27 | -10 | 24 |
| 20 |
|
FC Legnago Salus | 28 | 5 | 7 | 16 | 22:48 | -26 | 22 |
| Ascenso | |
| Playoff | |
| Permanencia | |
| Descenso |
