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| 20.03.2022 | 14:30 | FC Legnago Salus | - | Pro Vercelli | 0:1 (0:0) | |
| 14:30 | FC Südtirol | - | Seregno | 1:0 (0:0) | ||
| 14:30 | Trento Calcio 1921 | - | US Triestina | 2:1 (0:0) | ||
| 17:30 | Aurora Pro Patria | - | AC Renate | 1:0 (1:0) | ||
| 17:30 | Juventus II | - | Calcio Padova | 1:2 (1:1) | ||
| 17:30 | Piacenza Calcio | - | US Fiorenzuola | 0:1 (0:1) | ||
| 17:30 | AC Pro Sesto | - | Mantova 1911 SSD | 1:2 (0:0) | ||
| 17:30 | UC AlbinoLeffe | - | Calcio Lecco 1912 | 2:1 (1:0) | ||
| 17:30 | US Pergolettese | - | Giana Erminio | 2:0 (1:0) | ||
| 17:30 | Virtus Verona | - | FeralpiSalò | 1:0 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Südtirol | 33 | 25 | 7 | 1 | 42:7 | 35 | 82 |
| 2 |
|
Calcio Padova | 33 | 22 | 9 | 2 | 54:23 | 31 | 75 |
| 3 |
|
FeralpiSalò | 33 | 17 | 7 | 9 | 50:27 | 23 | 58 |
| 4 |
|
AC Renate | 33 | 16 | 7 | 10 | 51:37 | 14 | 55 |
| 5 |
|
Pro Vercelli | 33 | 13 | 12 | 8 | 36:30 | 6 | 51 |
| 6 |
|
Calcio Lecco 1912 | 33 | 15 | 5 | 13 | 46:36 | 10 | 50 |
| 7 |
|
US Triestina | 33 | 13 | 8 | 12 | 34:36 | -2 | 47 |
| 8 |
|
Juventus II | 33 | 13 | 7 | 13 | 36:37 | -1 | 46 |
| 9 |
|
Piacenza Calcio | 33 | 10 | 13 | 10 | 37:37 | 0 | 43 |
| 10 |
|
UC AlbinoLeffe | 33 | 9 | 13 | 11 | 36:36 | 0 | 40 |
| 11 |
|
Virtus Verona | 33 | 8 | 15 | 10 | 30:33 | -3 | 39 |
| 12 |
|
Mantova 1911 SSD | 33 | 8 | 14 | 11 | 30:33 | -3 | 38 |
| 13 |
|
Aurora Pro Patria | 33 | 8 | 14 | 11 | 33:41 | -8 | 38 |
| 14 |
|
US Fiorenzuola | 33 | 9 | 10 | 14 | 28:39 | -11 | 37 |
| 15 |
|
Trento Calcio 1921 | 33 | 8 | 12 | 13 | 26:32 | -6 | 36 |
| 16 |
|
US Pergolettese | 33 | 9 | 9 | 15 | 35:52 | -17 | 35 |
| 17 |
|
Seregno | 33 | 7 | 9 | 17 | 38:50 | -12 | 30 |
| 18 |
|
AC Pro Sesto | 33 | 6 | 12 | 15 | 29:43 | -14 | 30 |
| 19 |
|
Giana Erminio | 33 | 5 | 14 | 14 | 21:36 | -15 | 29 |
| 20 |
|
FC Legnago Salus | 33 | 6 | 9 | 18 | 26:53 | -27 | 27 |
| Ascenso | |
| Playoff | |
| Permanencia | |
| Descenso |
