 |
 |
|
|
| 04.09.2021 | 00:00 | Gallos Blancos | - | UANL Tigres | 1:2 (0:2) | |
| 17:00 | Mazatlán FC | - | FC Juárez | 1:2 (1:1) | ||
| 19:00 | Cruz Azul | - | Atlético San Luis | 2:0 (0:0) | ||
| 05.09.2021 | 01:10 | Deportivo Guadalajara | - | Atlas Guadalajara | 1:0 (0:0) | |
| 03:00 | CF América | - | Pumas UNAM | 2:2 (0:0) | ||
| 19:00 | Puebla FC | - | Santos Laguna | 2:3 (2:1) | ||
| 07.09.2021 | 00:00 | Deportivo Toluca | - | Club Necaxa | 0:1 (0:1) | |
| 02:00 | CF Pachuca | - | CF Monterrey | 0:1 (0:1) | ||
| 04:00 | Club Tijuana | - | Club León | 4:0 (2:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
UANL Tigres | 8 | 8 | 0 | 0 | 30:3 | 27 | 24 |
| 2 |
|
Deportivo Guadalajara | 8 | 7 | 1 | 0 | 20:3 | 17 | 22 |
| 3 |
|
CF Monterrey | 8 | 7 | 1 | 0 | 16:2 | 14 | 22 |
| 4 |
|
CF América | 8 | 6 | 1 | 1 | 19:7 | 12 | 19 |
| 5 |
|
Santos Laguna | 8 | 5 | 2 | 1 | 21:7 | 14 | 17 |
| 6 |
|
Club Tijuana | 8 | 4 | 3 | 1 | 12:4 | 8 | 15 |
| 7 |
|
Atlas Guadalajara | 8 | 3 | 2 | 3 | 11:12 | -1 | 11 |
| 8 |
|
Cruz Azul | 8 | 3 | 2 | 3 | 6:12 | -6 | 11 |
| 9 |
|
CF Pachuca | 8 | 2 | 3 | 3 | 12:11 | 1 | 9 |
| 10 |
|
Puebla FC | 8 | 3 | 0 | 5 | 12:16 | -4 | 9 |
| 11 |
|
Pumas UNAM | 8 | 1 | 4 | 3 | 7:10 | -3 | 7 |
| 12 |
|
Club León | 8 | 2 | 1 | 5 | 11:18 | -7 | 7 |
| 13 |
|
Deportivo Toluca | 8 | 2 | 1 | 5 | 7:14 | -7 | 7 |
| 14 |
|
Club Necaxa | 8 | 2 | 1 | 5 | 4:21 | -17 | 7 |
| 15 |
|
Gallos Blancos | 8 | 1 | 3 | 4 | 10:12 | -2 | 6 |
| 16 |
|
FC Juárez | 8 | 1 | 1 | 6 | 4:16 | -12 | 4 |
| 17 |
|
Atlético San Luis | 8 | 1 | 1 | 6 | 5:22 | -17 | 4 |
| 18 |
|
Mazatlán FC | 8 | 0 | 1 | 7 | 4:21 | -17 | 1 |
| Playoff |
