 |
 |
|
| 08.01.2022 | 03:00 | Mazatlán FC | - | Cruz Azul | 1:2 (1:0) | |
| 19:00 | Pumas UNAM | - | Club León | 1:0 (1:0) | ||
| 09.01.2022 | 19:00 | Puebla FC | - | Deportivo Toluca | 1:3 (0:2) | |
| 10.01.2022 | 03:00 | FC Juárez | - | Atlético San Luis | 0:1 (0:1) | |
| 11.01.2022 | 00:00 | Club Necaxa | - | UANL Tigres | 1:3 (0:2) | |
| 02:00 | CF América | - | Atlas Guadalajara | 1:1 (0:1) | ||
| 04:00 | CF Pachuca | - | Deportivo Guadalajara | 1:4 (1:3) | ||
| 04:00 | Club Tijuana | - | Santos Laguna | 2:1 (2:1) | ||
| 22.02.2022 | 04:00 | CF Monterrey | - | Gallos Blancos | 3:0 (3:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Deportivo Guadalajara | 1 | 1 | 0 | 0 | 4:1 | 3 | 3 |
| 2 |
|
CF Monterrey | 1 | 1 | 0 | 0 | 3:0 | 3 | 3 |
| 3 |
|
Deportivo Toluca | 1 | 1 | 0 | 0 | 3:1 | 2 | 3 |
|
UANL Tigres | 1 | 1 | 0 | 0 | 3:1 | 2 | 3 | |
| 5 |
|
Club Tijuana | 1 | 1 | 0 | 0 | 2:1 | 1 | 3 |
|
Cruz Azul | 1 | 1 | 0 | 0 | 2:1 | 1 | 3 | |
| 7 |
|
Atlético San Luis | 1 | 1 | 0 | 0 | 1:0 | 1 | 3 |
|
Pumas UNAM | 1 | 1 | 0 | 0 | 1:0 | 1 | 3 | |
| 9 |
|
Atlas Guadalajara | 1 | 0 | 1 | 0 | 1:1 | 0 | 1 |
|
CF América | 1 | 0 | 1 | 0 | 1:1 | 0 | 1 | |
| 11 |
|
Mazatlán FC | 1 | 0 | 0 | 1 | 1:2 | -1 | 0 |
|
Santos Laguna | 1 | 0 | 0 | 1 | 1:2 | -1 | 0 | |
| 13 |
|
Club León | 1 | 0 | 0 | 1 | 0:1 | -1 | 0 |
|
FC Juárez | 1 | 0 | 0 | 1 | 0:1 | -1 | 0 | |
| 15 |
|
Club Necaxa | 1 | 0 | 0 | 1 | 1:3 | -2 | 0 |
|
Puebla FC | 1 | 0 | 0 | 1 | 1:3 | -2 | 0 | |
| 17 |
|
CF Pachuca | 1 | 0 | 0 | 1 | 1:4 | -3 | 0 |
| 18 |
|
Gallos Blancos | 1 | 0 | 0 | 1 | 0:3 | -3 | 0 |
| Playoff |
