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| 30.03.2018 | 18:00 | Club León II | - | Atlas Guadalajara II | 1:3 | |
| 18:00 | Pumas UNAM II | - | CF América II | 1:2 | ||
| 18:00 | Lobos BUAP II | - | Sporting Canamy | 1:2 | ||
| 19:00 | CD Veracruz II | - | Halcones de Morelos | 3:0 | ||
| 20:00 | Gallos Blancos II | - | Cruz Azul II | 3:0 | ||
| 23:00 | Cruz Azul Hidalgo | - | Reboceros de La Piedad | 0:1 | ||
| 31.03.2018 | 03:00 | Tecos Fútbol Club | - | Club Tijuana II | 3:0 | |
| 03:00 | Atlético Reynosa | - | Dorados UACH | 4:0 | ||
| 05:30 | Deportivo Tepic | - | Santos Laguna II | 1:2 | ||
| 18:00 | Deportivo Toluca II | - | Pioneros de Cancún | 0:0 | ||
| 20:00 | Monarcas Morelia II | - | CF Monterrey II | 0:1 | ||
| 22:00 | Inter Playa | - | Real Zamora | 3:0 | ||
| 01.04.2018 | 00:00 | Tuxtla FC | - | CF Pachuca II | 3:0 | |
| 00:00 | Tepatitlán | - | UANL Tigres II | 0:0 | ||
| 01:00 | Gavilanes de Matamoros | - | Pacific F. C. | 2:1 | ||
| 18:00 | Club Necaxa II | - | Alacranes de Durango | 3:2 | ||
| 23:00 | Club Irapuato | - | Puebla FC II | 4:3 | ||
| 03.04.2018 | 00:00 | Loros UCOL | - | Deportivo Guadalajara II | 1:1 |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| 1 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Loros UCOL | 14 | 8 | 3 | 3 | 27:14 | 13 | 29 |
| 2 |
|
Club Necaxa II | 14 | 8 | 4 | 2 | 19:10 | 9 | 29 |
| 3 |
|
Atlas Guadalajara II | 14 | 6 | 5 | 3 | 20:17 | 3 | 24 |
| 4 |
|
Atlético Reynosa | 14 | 7 | 2 | 5 | 23:10 | 13 | 23 |
| 5 |
|
Tecos Fútbol Club | 14 | 6 | 4 | 4 | 16:11 | 5 | 22 |
| 6 |
|
Alacranes de Durango | 14 | 6 | 3 | 5 | 20:17 | 3 | 22 |
| 7 |
|
UANL Tigres II | 14 | 5 | 5 | 4 | 14:11 | 3 | 21 |
| 8 |
|
Tepatitlán | 14 | 5 | 4 | 5 | 16:15 | 1 | 20 |
| 9 |
|
Monarcas Morelia II | 14 | 4 | 6 | 4 | 15:16 | -1 | 19 |
| 10 |
|
Deportivo Tepic | 14 | 5 | 3 | 6 | 12:19 | -7 | 19 |
| 11 |
|
Santos Laguna II | 14 | 5 | 3 | 6 | 18:20 | -2 | 18 |
| 12 |
|
Club León II | 14 | 5 | 2 | 7 | 13:19 | -6 | 17 |
| 13 |
|
Pacific F. C. | 14 | 4 | 4 | 6 | 12:18 | -6 | 17 |
| 14 |
|
Deportivo Guadalajara II | 14 | 3 | 7 | 4 | 13:15 | -2 | 16 |
| 15 |
|
Gavilanes de Matamoros | 14 | 3 | 6 | 5 | 12:21 | -9 | 16 |
| 16 |
|
Club Tijuana II | 14 | 3 | 5 | 6 | 21:23 | -2 | 14 |
| 17 |
|
CF Monterrey II | 14 | 2 | 7 | 5 | 13:18 | -5 | 13 |
| 18 |
|
Dorados UACH | 14 | 3 | 3 | 8 | 15:25 | -10 | 12 |
| 2 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Tuxtla FC | 14 | 10 | 1 | 3 | 28:12 | 16 | 31 |
| 2 |
|
Reboceros de La Piedad | 14 | 9 | 2 | 3 | 24:14 | 10 | 30 |
| 3 |
|
Club Irapuato | 14 | 8 | 3 | 3 | 30:22 | 8 | 27 |
| 4 |
|
CF América II | 14 | 8 | 1 | 5 | 21:14 | 7 | 26 |
| 5 |
|
Inter Playa | 14 | 5 | 7 | 2 | 16:12 | 4 | 23 |
| 6 |
|
Pioneros de Cancún | 14 | 7 | 2 | 5 | 13:13 | 0 | 23 |
| 7 |
|
Real Zamora | 14 | 5 | 4 | 5 | 16:17 | -1 | 21 |
| 8 |
|
Gallos Blancos II | 14 | 4 | 6 | 4 | 19:15 | 4 | 19 |
| 9 |
|
Cruz Azul Hidalgo | 14 | 4 | 5 | 5 | 19:17 | 2 | 18 |
| 10 |
|
Sporting Canamy | 14 | 5 | 3 | 6 | 16:22 | -6 | 18 |
| 11 |
|
Lobos BUAP II | 14 | 3 | 7 | 4 | 15:20 | -5 | 17 |
| 12 |
|
CD Veracruz II | 14 | 4 | 4 | 6 | 13:13 | 0 | 16 |
| 13 |
|
Halcones de Morelos | 14 | 3 | 7 | 4 | 10:13 | -3 | 16 |
| 14 |
|
Puebla FC II | 14 | 3 | 5 | 6 | 15:20 | -5 | 15 |
| 15 |
|
Deportivo Toluca II | 14 | 3 | 5 | 6 | 14:19 | -5 | 15 |
| 16 |
|
Cruz Azul II | 14 | 3 | 4 | 7 | 16:24 | -8 | 14 |
| 17 |
|
Pumas UNAM II | 14 | 3 | 2 | 9 | 19:28 | -9 | 13 |
| 18 |
|
CF Pachuca II | 14 | 3 | 4 | 7 | 14:23 | -9 | 13 |
