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| 12.10.2018 | 23:00 | Club Necaxa II | - | Dorados UACH | 1:0 (1:0) | |
| 13.10.2018 | 02:30 | Atlético Reynosa | - | Tecos Fútbol Club | 3:0 (3:0) | |
| 03:00 | Murciélagos FC | - | Deportivo Guadalajara II | 0:1 (0:1) | ||
| 17:00 | Cimarrones de Sonora II | - | Coras de Nayarit | 1:2 (1:2) | ||
| 18:00 | Coyotes de Tlaxcala | - | Tuxtla FC | 3:0 (3:0) | ||
| 19:00 | Monarcas Morelia II | - | Pacific F. C. | 6:0 (6:0) | ||
| 23:00 | Cruz Azul Hidalgo | - | Albinegros Orizaba | 0:0 (0:0) | ||
| 23:00 | Real Zamora | - | CF América II | 2:0 (2:0) | ||
| 23:00 | Sporting Canamy | - | Inter Playa | 3:2 (3:2) | ||
| 23:00 | Tuzos de la UAZ | - | Club Irapuato | 3:2 (3:2) | ||
| 14.10.2018 | 00:00 | Gavilanes de Matamoros | - | Correcaminos UAT II | 3:1 (3:1) | |
| 00:00 | Yalmakan FC | - | Deportivo Toluca II | 2:2 (2:2) | ||
| 00:00 | Cocodrilos de Tabasco | - | Pumas UNAM II | 2:0 (2:0) | ||
| 03:00 | Reboceros de La Piedad | - | Pioneros de Cancún | 1:1 (1:1) | ||
| 19:00 | Leones Negros II | - | Alacranes de Durango | 5:0 (5:0) | ||
| 16.10.2018 | 00:00 | Tepatitlán | - | Loros UCOL | 0:3 (0:3) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Irapuato | 8 | 7 | 0 | 1 | 17:7 | 10 | 25 |
| 2 |
|
Deportivo Guadalajara II | 8 | 5 | 2 | 1 | 11:5 | 6 | 21 |
| 3 |
|
Tuxtla FC | 8 | 5 | 1 | 2 | 17:8 | 9 | 18 |
| 4 |
|
Deportivo Toluca II | 8 | 4 | 4 | 0 | 17:11 | 6 | 18 |
| 5 |
|
Inter Playa | 8 | 5 | 1 | 2 | 15:10 | 5 | 18 |
| 6 |
|
Gavilanes de Matamoros | 8 | 5 | 1 | 2 | 13:9 | 4 | 18 |
|
Tepatitlán | 8 | 5 | 1 | 2 | 13:9 | 4 | 18 | |
| 8 |
|
Loros UCOL | 8 | 3 | 2 | 3 | 15:9 | 6 | 17 |
| 9 |
|
Murciélagos FC | 8 | 4 | 2 | 2 | 13:8 | 5 | 17 |
| 10 |
|
Coras de Nayarit | 8 | 4 | 3 | 1 | 12:8 | 4 | 17 |
| 11 |
|
Cruz Azul Hidalgo | 8 | 4 | 1 | 3 | 11:8 | 3 | 17 |
| 12 |
|
Correcaminos UAT II | 8 | 3 | 4 | 1 | 11:7 | 4 | 16 |
| 13 |
|
Club Necaxa II | 8 | 3 | 4 | 1 | 7:7 | 0 | 16 |
| 14 |
|
Tuzos de la UAZ | 8 | 3 | 4 | 1 | 13:11 | 2 | 15 |
| 15 |
|
Dorados UACH | 8 | 3 | 2 | 3 | 8:11 | -3 | 15 |
| 16 |
|
Coyotes de Tlaxcala | 8 | 3 | 3 | 2 | 9:8 | 1 | 14 |
| 17 |
|
Pumas UNAM II | 8 | 3 | 0 | 5 | 10:10 | 0 | 12 |
| 18 |
|
Real Zamora | 8 | 3 | 0 | 5 | 10:15 | -5 | 11 |
| 19 |
|
Pacific F. C. | 8 | 2 | 3 | 3 | 11:18 | -7 | 11 |
| 20 |
|
Monarcas Morelia II | 8 | 2 | 3 | 3 | 16:7 | 9 | 10 |
| 21 |
|
Leones Negros II | 8 | 2 | 3 | 3 | 15:13 | 2 | 10 |
| 22 |
|
Atlético Reynosa | 8 | 1 | 3 | 4 | 7:8 | -1 | 10 |
| 23 |
|
Albinegros Orizaba | 8 | 2 | 3 | 3 | 4:6 | -2 | 10 |
| 24 |
|
Reboceros de La Piedad | 8 | 1 | 3 | 4 | 8:13 | -5 | 10 |
| 25 |
|
Tecos Fútbol Club | 8 | 1 | 2 | 5 | 6:13 | -7 | 10 |
| 26 |
|
Cocodrilos de Tabasco | 8 | 1 | 3 | 4 | 10:13 | -3 | 9 |
|
Pioneros de Cancún | 8 | 1 | 4 | 3 | 10:13 | -3 | 9 | |
| 28 |
|
CF América II | 8 | 1 | 4 | 3 | 9:15 | -6 | 9 |
| 29 |
|
Sporting Canamy | 8 | 2 | 2 | 4 | 9:17 | -8 | 9 |
| 30 |
|
Yalmakan FC | 8 | 1 | 3 | 4 | 5:9 | -4 | 8 |
| 31 |
|
Alacranes de Durango | 8 | 1 | 3 | 4 | 6:15 | -9 | 7 |
| 32 |
|
Cimarrones de Sonora II | 8 | 0 | 2 | 6 | 4:21 | -17 | 2 |
| Playoff | |
| Playoff | |
| Playoff | |
| Playoff | |
| Playoff | |
| Playoff | |
| Playoff | |
| Playoff | |
| Playoff | |
| Descenso |
