 |
 |
|
|
| 12.02.2022 | 02:00 | Mazatlán FC | - | Club Tijuana | 2:0 (1:0) | |
| 04:00 | Puebla FC | - | Atlas Guadalajara | 1:1 (0:0) | ||
| 13.02.2022 | 00:00 | Atlético San Luis | - | Deportivo Toluca | 0:1 (0:1) | |
| 00:00 | Deportivo Guadalajara | - | UANL Tigres | 1:3 (0:2) | ||
| 02:00 | Cruz Azul | - | Club Necaxa | 1:2 (1:0) | ||
| 04:00 | Santos Laguna | - | CF América | 2:3 (2:2) | ||
| 19:00 | Pumas UNAM | - | Club León | 2:1 (2:1) | ||
| 15.02.2022 | 04:00 | CF Pachuca | - | Gallos Blancos | 2:2 (2:1) | |
| 16.03.2022 | 04:06 | CF Monterrey | - | FC Juárez | 3:0 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Puebla FC | 5 | 3 | 2 | 0 | 9:3 | 6 | 11 |
| 2 |
|
Atlas Guadalajara | 5 | 3 | 2 | 0 | 7:3 | 4 | 11 |
| 3 |
|
CF Pachuca | 5 | 3 | 1 | 1 | 10:6 | 4 | 10 |
| 4 |
|
Cruz Azul | 5 | 3 | 1 | 1 | 7:4 | 3 | 10 |
| 5 |
|
UANL Tigres | 5 | 3 | 1 | 1 | 10:8 | 2 | 10 |
| 6 |
|
Deportivo Toluca | 5 | 3 | 1 | 1 | 8:9 | -1 | 10 |
| 7 |
|
CF Monterrey | 5 | 2 | 3 | 0 | 11:4 | 7 | 9 |
| 8 |
|
Pumas UNAM | 5 | 3 | 0 | 2 | 11:5 | 6 | 9 |
| 9 |
|
Deportivo Guadalajara | 5 | 2 | 1 | 2 | 9:7 | 2 | 7 |
| 10 |
|
Mazatlán FC | 5 | 2 | 0 | 3 | 8:10 | -2 | 6 |
| 11 |
|
Club Necaxa | 5 | 2 | 0 | 3 | 8:11 | -3 | 6 |
| 12 |
|
FC Juárez | 5 | 2 | 0 | 3 | 4:8 | -4 | 6 |
| 13 |
|
Club León | 5 | 1 | 2 | 2 | 5:6 | -1 | 5 |
| 14 |
|
CF América | 5 | 1 | 1 | 3 | 7:10 | -3 | 4 |
| 15 |
|
Club Tijuana | 5 | 1 | 1 | 3 | 3:8 | -5 | 4 |
| 16 |
|
Gallos Blancos | 5 | 0 | 3 | 2 | 4:8 | -4 | 3 |
| 17 |
|
Atlético San Luis | 5 | 1 | 0 | 4 | 3:7 | -4 | 3 |
| 18 |
|
Santos Laguna | 5 | 0 | 1 | 4 | 6:13 | -7 | 1 |
| Playoff | |
| Próxima ronda |
