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| 30.07.2022 | 16:00 | Deportivo Toluca | - | CF América | 2:5 (1:3) | |
| 16:00 | Pumas UNAM | - | CF Pachuca | 2:1 (1:1) | ||
| 16:00 | Gallos Blancos | - | Puebla FC | 2:1 (2:1) | ||
| 16:00 | Atlético San Luis | - | UANL Tigres | 2:5 (2:3) | ||
| 18:30 | Club Necaxa | - | FC Juárez | 1:0 (0:0) | ||
| 19:00 | Club Tijuana | - | Deportivo Guadalajara | 2:2 (1:1) | ||
| 19:30 | Mazatlán FC | - | Atlas Guadalajara | 1:0 (1:0) | ||
| 23:00 | CF Monterrey | - | Club León | 3:0 (2:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| 1 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Necaxa | 5 | 3 | 2 | 0 | 15:5 | 10 | 11 |
| 2 |
|
CF América | 5 | 3 | 1 | 1 | 13:9 | 4 | 10 |
| 3 |
|
CF Pachuca | 6 | 3 | 1 | 2 | 9:9 | 0 | 10 |
| 4 |
|
Pumas UNAM | 5 | 2 | 2 | 1 | 5:6 | -1 | 8 |
| 5 |
|
Deportivo Toluca | 5 | 2 | 1 | 2 | 14:11 | 3 | 7 |
| 6 |
|
Gallos Blancos | 6 | 2 | 1 | 3 | 7:13 | -6 | 7 |
| 7 |
|
Cruz Azul | 5 | 1 | 2 | 2 | 10:8 | 2 | 5 |
| 8 |
|
FC Juárez | 6 | 1 | 2 | 3 | 5:10 | -5 | 5 |
| 9 |
|
Puebla FC | 5 | 0 | 2 | 3 | 5:12 | -7 | 2 |
| 2 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Monterrey | 6 | 4 | 0 | 2 | 12:7 | 5 | 12 |
| 2 |
|
Santos Laguna | 5 | 4 | 0 | 1 | 10:6 | 4 | 12 |
| 3 |
|
Deportivo Guadalajara | 5 | 3 | 1 | 1 | 11:7 | 4 | 10 |
| 4 |
|
Mazatlán FC | 5 | 3 | 1 | 1 | 7:5 | 2 | 10 |
| 5 |
|
Club Tijuana | 6 | 2 | 2 | 2 | 7:6 | 1 | 8 |
| 6 |
|
Atlas Guadalajara | 6 | 2 | 1 | 3 | 5:7 | -2 | 7 |
| 7 |
|
UANL Tigres | 5 | 2 | 0 | 3 | 7:9 | -2 | 6 |
| 8 |
|
Atlético San Luis | 5 | 1 | 1 | 3 | 9:13 | -4 | 4 |
| 9 |
|
Club León | 5 | 0 | 0 | 5 | 3:11 | -8 | 0 |
| Playoff | |
| Playoff |
