 |
 |
|
|
| 02.04.2021 | 19:45 | Puebla FC | - | Mazatlán FC | 3:0 (1:0) | |
| 20:30 | FC Juárez | - | Cruz Azul | 2:0 (1:0) | ||
| 03.04.2021 | 17:00 | CF América | - | Club Necaxa | 1:2 (0:1) | |
| 19:30 | Atlas Guadalajara | - | Club Tijuana | 2:1 (1:0) | ||
| 19:30 | CF Monterrey | - | Atlético San Luis | 4:1 (1:1) | ||
| 04.04.2021 | 18:15 | Deportivo Guadalajara | - | Santos Laguna | 2:0 (2:0) | |
| 18:30 | Pumas UNAM | - | CF Pachuca | 5:3 (1:3) | ||
| 18:30 | Gallos Blancos | - | UANL Tigres | 1:0 (0:0) | ||
| 18:30 | Club León | - | Deportivo Toluca | 2:0 (1:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Pachuca | 13 | 8 | 3 | 2 | 35:19 | 16 | 40 |
| 2 |
|
Atlas Guadalajara | 13 | 8 | 1 | 4 | 24:18 | 6 | 37 |
| 3 |
|
Club León | 13 | 8 | 3 | 2 | 25:16 | 9 | 34 |
| 4 |
|
Deportivo Guadalajara | 13 | 7 | 4 | 2 | 24:13 | 11 | 32 |
| 5 |
|
Santos Laguna | 13 | 7 | 2 | 4 | 26:21 | 5 | 32 |
| 6 |
|
UANL Tigres | 13 | 7 | 3 | 3 | 21:13 | 8 | 31 |
| 7 |
|
Pumas UNAM | 13 | 6 | 2 | 5 | 20:15 | 5 | 28 |
| 8 |
|
Club Tijuana | 13 | 6 | 1 | 6 | 22:21 | 1 | 28 |
| 9 |
|
CF Monterrey | 13 | 6 | 2 | 5 | 21:18 | 3 | 27 |
| 10 |
|
Mazatlán FC | 13 | 4 | 4 | 5 | 16:24 | -8 | 26 |
| 11 |
|
Puebla FC | 13 | 5 | 3 | 5 | 21:19 | 2 | 25 |
| 12 |
|
Deportivo Toluca | 13 | 4 | 5 | 4 | 20:19 | 1 | 25 |
| 13 |
|
Cruz Azul | 13 | 5 | 1 | 7 | 19:22 | -3 | 24 |
| 14 |
|
Club Necaxa | 13 | 4 | 2 | 7 | 18:21 | -3 | 24 |
| 15 |
|
FC Juárez | 13 | 5 | 1 | 7 | 17:17 | 0 | 23 |
| 16 |
|
Atlético San Luis | 13 | 1 | 2 | 10 | 11:37 | -26 | 17 |
| 17 |
|
Gallos Blancos | 13 | 3 | 1 | 9 | 17:28 | -11 | 16 |
| 18 |
|
CF América | 13 | 3 | 0 | 10 | 15:31 | -16 | 15 |
| Playoff |
