 |
 |
|
|
| 25.02.2021 | 19:00 | Atlético San Luis | - | UANL Tigres | 2:2 (2:1) | |
| 26.02.2021 | 18:45 | Puebla FC | - | Club Necaxa | 1:0 (1:0) | |
| 27.02.2021 | 16:00 | CF América | - | CF Pachuca | 0:3 (0:2) | |
| 18:30 | Deportivo Toluca | - | Atlas Guadalajara | 1:2 (0:1) | ||
| 18:30 | Club León | - | Cruz Azul | 2:1 (1:0) | ||
| 28.02.2021 | 16:00 | Santos Laguna | - | FC Juárez | 3:2 (0:1) | |
| 18:15 | Deportivo Guadalajara | - | Pumas UNAM | 1:0 (0:0) | ||
| 18:30 | CF Monterrey | - | Club Tijuana | 3:2 (1:2) | ||
| 26.03.2021 | 19:30 | Mazatlán FC | - | Gallos Blancos | 2:0 (2:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Pachuca | 8 | 6 | 1 | 1 | 22:9 | 13 | 32 |
| 2 |
|
UANL Tigres | 8 | 7 | 1 | 0 | 15:4 | 11 | 29 |
| 3 |
|
Santos Laguna | 8 | 6 | 1 | 1 | 21:12 | 9 | 28 |
| 4 |
|
Atlas Guadalajara | 8 | 4 | 1 | 3 | 14:14 | 0 | 25 |
| 5 |
|
CF Monterrey | 8 | 5 | 1 | 2 | 16:12 | 4 | 23 |
| 6 |
|
Club León | 8 | 4 | 2 | 2 | 13:10 | 3 | 21 |
| 7 |
|
Deportivo Guadalajara | 8 | 3 | 4 | 1 | 14:9 | 5 | 20 |
| 8 |
|
Mazatlán FC | 8 | 2 | 4 | 2 | 10:11 | -1 | 20 |
| 9 |
|
Club Tijuana | 8 | 3 | 1 | 4 | 11:13 | -2 | 19 |
| 10 |
|
Club Necaxa | 8 | 2 | 2 | 4 | 14:14 | 0 | 18 |
| 11 |
|
Cruz Azul | 8 | 3 | 1 | 4 | 11:16 | -5 | 18 |
| 12 |
|
Deportivo Toluca | 8 | 2 | 3 | 3 | 12:13 | -1 | 17 |
| 13 |
|
Puebla FC | 8 | 3 | 1 | 4 | 10:12 | -2 | 17 |
| 14 |
|
FC Juárez | 8 | 3 | 0 | 5 | 12:13 | -1 | 16 |
| 15 |
|
Pumas UNAM | 8 | 2 | 1 | 5 | 7:9 | -2 | 15 |
| 16 |
|
Atlético San Luis | 8 | 0 | 2 | 6 | 6:20 | -14 | 14 |
| 17 |
|
CF América | 8 | 2 | 0 | 6 | 10:18 | -8 | 12 |
| 18 |
|
Gallos Blancos | 8 | 2 | 0 | 6 | 8:17 | -9 | 12 |
| Playoff |
