 |
 |
|
|
| 20.01.2022 | 18:30 | Atlético San Luis | - | FC Juárez | 1:1 (0:0) | |
| 21.01.2022 | 18:15 | Puebla FC | - | Club Tijuana | 1:1 (0:0) | |
| 19:30 | Mazatlán FC | - | Deportivo Toluca | 0:0 (0:0) | ||
| 22.01.2022 | 18:00 | CF América | - | Atlas Guadalajara | 0:0 (0:0) | |
| 18:15 | Deportivo Guadalajara | - | Gallos Blancos | 1:0 (0:0) | ||
| 18:30 | Club León | - | CF Pachuca | 4:2 (1:1) | ||
| 18:30 | CF Monterrey | - | Cruz Azul | 1:0 (1:0) | ||
| 23.01.2022 | 16:00 | Santos Laguna | - | Club Necaxa | 1:2 (0:2) | |
| 18:30 | Pumas UNAM | - | UANL Tigres | 1:4 (1:2) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Monterrey | 3 | 3 | 0 | 0 | 8:3 | 5 | 20 |
| 2 |
|
Atlas Guadalajara | 3 | 2 | 1 | 0 | 2:0 | 2 | 18 |
| 3 |
|
CF América | 3 | 2 | 1 | 0 | 4:0 | 4 | 17 |
| 4 |
|
Cruz Azul | 3 | 2 | 0 | 1 | 4:3 | 1 | 15 |
| 5 |
|
UANL Tigres | 3 | 2 | 0 | 1 | 5:6 | -1 | 15 |
| 6 |
|
Deportivo Guadalajara | 3 | 2 | 0 | 1 | 7:5 | 2 | 14 |
| 7 |
|
Santos Laguna | 3 | 1 | 1 | 1 | 8:4 | 4 | 13 |
| 8 |
|
Club León | 3 | 2 | 0 | 1 | 6:4 | 2 | 13 |
| 9 |
|
Pumas UNAM | 3 | 2 | 0 | 1 | 5:4 | 1 | 13 |
| 10 |
|
Club Tijuana | 3 | 0 | 1 | 2 | 4:6 | -2 | 12 |
| 11 |
|
FC Juárez | 3 | 1 | 1 | 1 | 6:5 | 1 | 11 |
| 12 |
|
Mazatlán FC | 3 | 0 | 1 | 2 | 1:7 | -6 | 11 |
| 13 |
|
Atlético San Luis | 3 | 1 | 1 | 1 | 2:2 | 0 | 10 |
| 14 |
|
CF Pachuca | 3 | 1 | 0 | 2 | 6:7 | -1 | 10 |
| 15 |
|
Deportivo Toluca | 3 | 0 | 2 | 1 | 2:3 | -1 | 10 |
| 16 |
|
Puebla FC | 3 | 0 | 1 | 2 | 1:3 | -2 | 10 |
| 17 |
|
Club Necaxa | 3 | 1 | 0 | 2 | 6:10 | -4 | 10 |
| 18 |
|
Gallos Blancos | 3 | 0 | 0 | 3 | 2:7 | -5 | 7 |
| Playoff |
