 |
 |
|
| 29.04.2021 | 17:00 | Atlético San Luis | - | CF Pachuca | 2:0 (0:0) | |
| 30.04.2021 | 16:00 | Club Necaxa | - | Atlas Guadalajara | 2:2 (0:1) | |
| 17:00 | FC Juárez | - | Deportivo Toluca | 0:0 (0:0) | ||
| 01.05.2021 | 16:00 | Deportivo Guadalajara | - | UANL Tigres | 1:1 (0:0) | |
| 16:00 | Cruz Azul | - | Club Tijuana | 0:1 (0:1) | ||
| 16:00 | CF Monterrey | - | Mazatlán FC | 2:0 (2:0) | ||
| 16:00 | Club León | - | Gallos Blancos | 3:0 (1:0) | ||
| 18:30 | Pumas UNAM | - | CF América | 0:1 (0:0) | ||
| 02.05.2021 | 18:00 | Santos Laguna | - | Puebla FC | 2:3 (1:2) |
| » Clasificación | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Monterrey | 17 | 11 | 2 | 4 | 30:18 | 12 | 35 |
| 2 |
|
CF Pachuca | 17 | 10 | 4 | 3 | 37:22 | 15 | 34 |
| 3 |
|
CF América | 17 | 10 | 3 | 4 | 29:13 | 16 | 33 |
| 4 |
|
Club Tijuana | 17 | 10 | 1 | 6 | 26:16 | 10 | 31 |
| 5 |
|
Deportivo Toluca | 17 | 8 | 4 | 5 | 29:20 | 9 | 28 |
| 6 |
|
Atlas Guadalajara | 17 | 8 | 4 | 5 | 25:19 | 6 | 28 |
| 7 |
|
FC Juárez | 17 | 7 | 5 | 5 | 19:19 | 0 | 26 |
| 8 |
|
Club León | 17 | 8 | 2 | 7 | 26:29 | -3 | 26 |
| 9 |
|
Puebla FC | 17 | 8 | 0 | 9 | 35:42 | -7 | 24 |
| 10 |
|
UANL Tigres | 17 | 6 | 5 | 6 | 27:20 | 7 | 23 |
| 11 |
|
Mazatlán FC | 17 | 6 | 4 | 7 | 26:30 | -4 | 22 |
| 12 |
|
Atlético San Luis | 17 | 7 | 1 | 9 | 25:34 | -9 | 22 |
| 13 |
|
Santos Laguna | 17 | 5 | 5 | 7 | 27:24 | 3 | 20 |
| 14 |
|
Deportivo Guadalajara | 17 | 6 | 2 | 9 | 28:29 | -1 | 20 |
| 15 |
|
Club Necaxa | 17 | 4 | 4 | 9 | 19:26 | -7 | 16 |
| 16 |
|
Pumas UNAM | 17 | 4 | 4 | 9 | 24:34 | -10 | 16 |
| 17 |
|
Cruz Azul | 17 | 4 | 3 | 10 | 11:27 | -16 | 15 |
| 18 |
|
Gallos Blancos | 17 | 4 | 1 | 12 | 13:34 | -21 | 13 |
| Playoff |
