20.11.2021 14:00 Mosta FC - Gżira United 2:2 (1:2)
16:00 Sliema Wanderers - Valletta FC 2:1 (0:1)
18:00 Gudja United - Floriana FC 0:1 (0:0)
21.11.2021 11:30 St. Luċija FC - Birkirkara FC 2:0 (2:0)
14:00 Sirens FC - Balzan FC 1:6 (0:5)
18:00 Hibernians FC - Hamrun Spartans 1:0 (1:0)
# Equipo P V E D Goles DG Pun.
1 Hibernians FC, Malta Hibernians FC 9 6 3 0 18:8 10 21
2 Floriana FC, Malta Floriana FC 9 4 4 1 13:8 5 16
3 Balzan FC, Malta Balzan FC 9 5 0 4 14:9 5 15
4 Birkirkara FC, Malta Birkirkara FC 9 4 3 2 14:10 4 15
5 Valletta FC, Malta Valletta FC 9 4 1 4 13:15 -2 13
6 Hamrun Spartans, Malta Hamrun Spartans 9 4 0 5 10:10 0 12
7 Sirens FC, Malta Sirens FC 9 3 2 4 13:19 -6 11
8 Gżira United, Malta Gżira United 9 2 4 3 11:12 -1 10
9 Mosta FC, Malta Mosta FC 9 2 4 3 14:17 -3 10
10 St. Luċija FC, Malta St. Luċija FC 9 1 6 2 14:16 -2 9
11 Gudja United, Malta Gudja United 9 2 1 6 9:14 -5 7
  Sliema Wanderers, Malta Sliema Wanderers 9 1 4 4 9:14 -5 7
  Playoff
  Permanencia