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| 31.10.2020 | 18:45 | FC Twente | - | PEC Zwolle | 5:1 (3:0) | |
| 20:00 | AFC Ajax | - | Fortuna Sittard | 5:2 (2:1) | ||
| 20:00 | FC Groningen | - | VVV-Venlo | 2:1 (1:0) | ||
| 21:00 | Willem II | - | Vitesse | 1:3 (1:0) | ||
| 01.11.2020 | 12:15 | Heracles Almelo | - | FC Utrecht | 4:1 (2:0) | |
| 14:30 | Sparta Rotterdam | - | sc Heerenveen | 1:4 (0:3) | ||
| 14:30 | FC Emmen | - | Feyenoord | 2:3 (2:2) | ||
| 16:45 | PSV | - | ADO Den Haag | 4:0 (1:0) | ||
| 20:00 | AZ Alkmaar | - | RKC Waalwijk | 3:0 (1:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta | 1.ª parte | 2.ª parte |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
AFC Ajax | 7 | 6 | 0 | 1 | 29:5 | 24 | 18 |
| 2 |
|
Vitesse | 7 | 6 | 0 | 1 | 14:4 | 10 | 18 |
| 3 |
|
PSV | 7 | 5 | 1 | 1 | 16:5 | 11 | 16 |
| 4 |
|
sc Heerenveen | 7 | 5 | 1 | 1 | 16:8 | 8 | 16 |
| 5 |
|
Feyenoord | 7 | 4 | 3 | 0 | 17:9 | 8 | 15 |
| 6 |
|
FC Twente | 7 | 4 | 2 | 1 | 16:6 | 10 | 14 |
| 7 |
|
FC Groningen | 7 | 4 | 1 | 2 | 9:8 | 1 | 13 |
| 8 |
|
FC Utrecht | 7 | 2 | 4 | 1 | 10:10 | 0 | 10 |
| 9 |
|
AZ Alkmaar | 7 | 1 | 6 | 0 | 17:14 | 3 | 9 |
| 10 |
|
Heracles Almelo | 7 | 2 | 2 | 3 | 8:11 | -3 | 8 |
| 11 |
|
PEC Zwolle | 7 | 1 | 3 | 3 | 7:12 | -5 | 6 |
| 12 |
|
Willem II | 7 | 1 | 2 | 4 | 7:13 | -6 | 5 |
| 13 |
|
RKC Waalwijk | 7 | 1 | 2 | 4 | 5:13 | -8 | 5 |
| 14 |
|
VVV-Venlo | 7 | 1 | 2 | 4 | 10:24 | -14 | 5 |
| 15 |
|
ADO Den Haag | 7 | 1 | 1 | 5 | 6:16 | -10 | 4 |
| 16 |
|
FC Emmen | 7 | 0 | 3 | 4 | 10:18 | -8 | 3 |
| 17 |
|
Sparta Rotterdam | 7 | 0 | 3 | 4 | 7:17 | -10 | 3 |
| 18 |
|
Fortuna Sittard | 7 | 0 | 2 | 5 | 9:20 | -11 | 2 |
| Champions League | |
| CL Ronda previa | |
| Europa League | |
| Playoff | |
| Descenso | |
| Descenso |
