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| 02.09.2022 | 20:00 | Fortuna Sittard | - | FC Utrecht | 3:4 (0:0) | |
| 03.09.2022 | 16:30 | AFC Ajax | - | SC Cambuur | 4:0 (2:0) | |
| 18:45 | FC Twente | - | PSV | 2:1 (2:0) | ||
| 20:00 | Sparta Rotterdam | - | FC Volendam | 4:0 (1:0) | ||
| 21:00 | Go Ahead Eagles | - | Feyenoord | 3:4 (2:2) | ||
| 04.09.2022 | 12:15 | RKC Waalwijk | - | SBV Excelsior | 5:2 (1:2) | |
| 14:30 | FC Emmen | - | AZ Alkmaar | 0:3 (0:3) | ||
| 14:30 | sc Heerenveen | - | NEC Nijmegen | 0:0 (0:0) | ||
| 16:45 | FC Groningen | - | Vitesse | 0:1 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta | 1.ª parte | 2.ª parte |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
AFC Ajax | 5 | 5 | 0 | 0 | 16:3 | 13 | 15 |
| 2 |
|
Feyenoord | 5 | 4 | 1 | 0 | 14:5 | 9 | 13 |
| 3 |
|
AZ Alkmaar | 5 | 4 | 1 | 0 | 10:3 | 7 | 13 |
| 4 |
|
PSV | 5 | 4 | 0 | 1 | 23:7 | 16 | 12 |
| 5 |
|
FC Twente | 5 | 4 | 0 | 1 | 10:2 | 8 | 12 |
| 6 |
|
sc Heerenveen | 5 | 2 | 3 | 0 | 6:1 | 5 | 9 |
| 7 |
|
Sparta Rotterdam | 5 | 2 | 1 | 2 | 7:4 | 3 | 7 |
| 8 |
|
RKC Waalwijk | 5 | 1 | 3 | 1 | 10:8 | 2 | 6 |
| 9 |
|
NEC Nijmegen | 5 | 1 | 3 | 1 | 6:4 | 2 | 6 |
| 10 |
|
SBV Excelsior | 5 | 2 | 0 | 3 | 8:16 | -8 | 6 |
| 11 |
|
FC Utrecht | 5 | 1 | 2 | 2 | 8:10 | -2 | 5 |
| 12 |
|
FC Groningen | 5 | 1 | 2 | 2 | 5:10 | -5 | 5 |
| 13 |
|
SC Cambuur | 5 | 1 | 1 | 3 | 4:8 | -4 | 4 |
| 14 |
|
Vitesse | 5 | 1 | 1 | 3 | 6:14 | -8 | 4 |
| 15 |
|
FC Emmen | 5 | 1 | 1 | 3 | 5:14 | -9 | 4 |
| 16 |
|
FC Volendam | 5 | 1 | 1 | 3 | 5:17 | -12 | 4 |
| 17 |
|
Go Ahead Eagles | 5 | 0 | 0 | 5 | 5:13 | -8 | 0 |
| 18 |
|
Fortuna Sittard | 5 | 0 | 0 | 5 | 7:16 | -9 | 0 |
| Champions League | |
| CL Ronda previa | |
| EL Ronda previa | |
| ECL Ronda previa | |
| Playoff | |
| Permanencia | |
| Descenso |
