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| 17.10.2021 | 15:00 | Viktoria Arnoldsweiler | - | Siegburger SV 04 | 1:3 (0:2) | |
| 15:00 | SV 1914 Eilendorf | - | Spvg Wesseling-Urfeld | 1:3 (1:2) | ||
| 15:00 | FC Hürth | - | SV Deutz 05 | 3:1 (0:0) | ||
| 15:00 | FC Hennef 05 | - | 1. FC Düren | 0:2 (0:1) | ||
| 15:00 | SV Bergisch Gladbach 09 | - | SV Breinig | 8:0 (4:0) | ||
| 15:00 | Borussia Freialdenhoven | - | FC Pesch 1956 | 0:1 (0:0) | ||
| 15:30 | Blau-Weiß Friesdorf | - | BC Viktoria Glesch-Paffendorf | 1:4 (1:2) | ||
| 15:30 | SpVg Frechen 20 | - | VfL Alfter | 0:0 (0:0) | ||
| 15:30 | VfL 08 Vichttal | - | Fortuna Köln II | 3:0 (1:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
1. FC Düren | 11 | 9 | 2 | 0 | 36:6 | 30 | 29 |
| 2 |
|
FC Hennef 05 | 11 | 8 | 2 | 1 | 27:6 | 21 | 26 |
| 3 |
|
SpVg Frechen 20 | 11 | 7 | 2 | 2 | 24:8 | 16 | 23 |
| 4 |
|
SV Bergisch Gladbach 09 | 11 | 6 | 4 | 1 | 31:7 | 24 | 22 |
| 5 |
|
Borussia Freialdenhoven | 11 | 7 | 1 | 3 | 20:11 | 9 | 22 |
| 6 |
|
Siegburger SV 04 | 11 | 5 | 4 | 2 | 15:10 | 5 | 19 |
| 7 |
|
FC Hürth | 11 | 6 | 1 | 4 | 18:19 | -1 | 19 |
| 8 |
|
VfL Alfter | 11 | 5 | 3 | 3 | 17:17 | 0 | 18 |
| 9 |
|
FC Pesch 1956 | 11 | 4 | 5 | 2 | 21:10 | 11 | 17 |
| 10 |
|
BC Viktoria Glesch-Paffendorf | 11 | 5 | 2 | 4 | 18:14 | 4 | 17 |
| 11 |
|
VfL 08 Vichttal | 11 | 5 | 2 | 4 | 19:20 | -1 | 17 |
| 12 |
|
Viktoria Arnoldsweiler | 11 | 5 | 1 | 5 | 21:19 | 2 | 16 |
| 13 |
|
Blau-Weiß Friesdorf | 11 | 3 | 3 | 5 | 15:21 | -6 | 12 |
| 14 |
|
SV Deutz 05 | 11 | 2 | 2 | 7 | 11:28 | -17 | 8 |
| 15 |
|
Spvg Wesseling-Urfeld | 11 | 2 | 0 | 9 | 11:35 | -24 | 6 |
| 16 |
|
Fortuna Köln II | 11 | 1 | 2 | 8 | 8:25 | -17 | 5 |
| 17 |
|
SV 1914 Eilendorf | 11 | 1 | 0 | 10 | 5:29 | -24 | 3 |
| 18 |
|
SV Breinig | 11 | 0 | 0 | 11 | 5:37 | -32 | 0 |
| Playoff | |
| Descenso |
