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| 07.05.2022 | 13:00 | FSV Budissa Bautzen | - | Blau-Weiß Zorbau | 1:3 (1:1) | |
| 14:00 | FSV Martinroda | - | Bischofswerdaer FV | 1:5 (0:1) | ||
| 14:00 | Union Sandersdorf | - | FC Einheit Rudolstadt | 0:0 (0:0) | ||
| 14:00 | VfB 1921 Krieschow | - | FC An der Fahner Höhe | 4:0 (2:0) | ||
| 08.05.2022 | VFC Plauen | - | 1. FC Merseburg | no jug. | ||
| 13:00 | FC Carl Zeiss Jena II | - | FC Oberlausitz | 1:2 (1:1) | ||
| 14:00 | Einheit Wernigerode | - | SV 09 Arnstadt | 5:1 (2:1) | ||
| 14:00 | Rot-Weiß Erfurt | - | VfL Halle 96 | 3:0 (2:0) | ||
| 14:00 | FC Grimma | - | Wacker Nordhausen | 1:0 (1:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | ∅ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Rot-Weiß Erfurt | 25 | 21 | 3 | 1 | 83:14 | 69 | 66 | 2.64 |
| 2 |
|
VFC Plauen | 24 | 14 | 7 | 3 | 48:19 | 29 | 49 | 2.04 |
| 3 |
|
VfB 1921 Krieschow | 24 | 13 | 6 | 5 | 51:29 | 22 | 45 | 1.88 |
| 4 |
|
FSV Budissa Bautzen | 24 | 14 | 1 | 9 | 61:48 | 13 | 43 | 1.79 |
| 5 |
|
FC Carl Zeiss Jena II | 24 | 10 | 6 | 8 | 40:34 | 6 | 36 | 1.50 |
| 6 |
|
VfL Halle 96 | 24 | 9 | 9 | 6 | 40:35 | 5 | 36 | 1.50 |
| 7 |
|
FC Oberlausitz | 23 | 10 | 3 | 10 | 34:32 | 2 | 33 | 1.43 |
| 8 |
|
Einheit Wernigerode | 24 | 9 | 7 | 8 | 43:40 | 3 | 34 | 1.42 |
| 9 |
|
Union Sandersdorf | 25 | 9 | 7 | 9 | 37:29 | 8 | 34 | 1.36 |
| 10 |
|
FC Einheit Rudolstadt | 25 | 9 | 7 | 9 | 34:41 | -7 | 34 | 1.36 |
| 11 |
|
Bischofswerdaer FV | 25 | 8 | 9 | 8 | 38:40 | -2 | 33 | 1.32 |
| 12 |
|
FC An der Fahner Höhe | 24 | 9 | 3 | 12 | 24:32 | -8 | 30 | 1.25 |
| 13 |
|
FC Grimma | 25 | 7 | 6 | 12 | 39:43 | -4 | 27 | 1.08 |
| 14 |
|
Blau-Weiß Zorbau | 25 | 6 | 9 | 10 | 33:56 | -23 | 27 | 1.08 |
| 15 |
|
Wacker Nordhausen | 24 | 6 | 7 | 11 | 27:44 | -17 | 25 | 1.04 |
| 16 |
|
Inter Leipzig | 23 | 6 | 4 | 13 | 32:50 | -18 | 22 | 0.96 |
| 17 |
|
SV 09 Arnstadt | 23 | 2 | 8 | 13 | 19:60 | -41 | 14 | 0.61 |
| 18 |
|
FSV Martinroda | 25 | 3 | 4 | 18 | 25:62 | -37 | 13 | 0.52 |
| 19 |
|
1. FC Merseburg | 0 | 0 | 0 | 0 | 0:0 | 0 | 0 | |
| Ascenso | |
| Descenso |
