 |
 |
|
|
| 12.06.2022 | 22:30 | Guaireña FC | - | General Caballero DJLM | 1:2 (0:1) | |
| 13.06.2022 | 00:45 | Sol de América | - | 12 de Octubre de Itauguá | 0:0 (0:0) | |
| 23:00 | Club Nacional | - | Tacuary | 3:0 (1:0) | ||
| 14.06.2022 | 01:15 | Guaraní | - | Libertad | 1:1 (0:1) | |
| 23:00 | Sportivo Ameliano | - | Club Olimpia | 1:4 (0:1) | ||
| 15.06.2022 | 01:15 | Cerro Porteño | - | Resistencia SC | 1:0 (1:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Libertad | 18 | 14 | 3 | 1 | 39:14 | 25 | 45 |
| 2 |
|
Cerro Porteño | 18 | 13 | 2 | 3 | 33:11 | 22 | 41 |
| 3 |
|
Club Olimpia | 18 | 10 | 3 | 5 | 28:20 | 8 | 33 |
| 4 |
|
Resistencia SC | 18 | 7 | 7 | 4 | 28:23 | 5 | 28 |
| 5 |
|
Guaraní | 18 | 7 | 4 | 7 | 26:21 | 5 | 25 |
| 6 |
|
Club Nacional | 18 | 7 | 2 | 9 | 23:27 | -4 | 23 |
| 7 |
|
Sol de América | 18 | 6 | 5 | 7 | 17:21 | -4 | 23 |
| 8 |
|
Guaireña FC | 18 | 5 | 5 | 8 | 18:21 | -3 | 20 |
| 9 |
|
Tacuary | 18 | 6 | 2 | 10 | 14:24 | -10 | 20 |
| 10 |
|
General Caballero DJLM | 18 | 4 | 4 | 10 | 16:27 | -11 | 16 |
| 11 |
|
12 de Octubre de Itauguá | 18 | 2 | 8 | 8 | 13:32 | -19 | 14 |
| 12 |
|
Sportivo Ameliano | 18 | 4 | 1 | 13 | 19:33 | -14 | 13 |
| Copa Libertadores |
