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| 11.03.2022 | 19:00 | SpVgg Unterhaching | - | Bayern Múnich II | 0:3 (0:1) | |
| 19:00 | Viktoria Aschaffenburg | - | SV Heimstetten | 0:2 (0:1) | ||
| 12.03.2022 | 13:00 | TSV 1860 Rosenheim | - | FC Memmingen | 1:1 (1:0) | |
| 14:00 | 1. FC Schweinfurt 05 | - | SC Eltersdorf | 4:2 (2:1) | ||
| 14:00 | SpVgg Bayreuth | - | VfB Eichstätt | 4:1 (2:1) | ||
| 14:00 | SV Schalding-Heining | - | FC Pipinsried | 0:1 (0:0) | ||
| 14:00 | TSV Aubstadt | - | FV Illertissen | 1:1 (0:0) | ||
| 22.03.2022 | 19:00 | SpVgg Greuther Fürth II | - | Wacker Burghausen | 1:1 (1:1) | |
| 03.05.2022 | 18:30 | TSV 1896 Rain | - | 1. FC Nürnberg II | 1:1 (1:1) | |
| 19:00 | TSV Buchbach | - | Augsburgo II | 0:1 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta | 1.ª parte | 2.ª parte |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SpVgg Bayreuth | 28 | 23 | 2 | 3 | 76:25 | 51 | 71 |
| 2 |
|
Bayern Múnich II | 28 | 19 | 7 | 2 | 87:33 | 54 | 64 |
| 3 |
|
FV Illertissen | 28 | 15 | 7 | 6 | 49:28 | 21 | 52 |
| 4 |
|
1. FC Schweinfurt 05 | 28 | 14 | 9 | 5 | 83:37 | 46 | 51 |
| 5 |
|
Wacker Burghausen | 28 | 14 | 5 | 9 | 61:42 | 19 | 47 |
| 6 |
|
TSV Aubstadt | 28 | 12 | 9 | 7 | 50:32 | 18 | 45 |
| 7 |
|
SpVgg Unterhaching | 28 | 12 | 7 | 9 | 54:51 | 3 | 43 |
| 8 |
|
VfB Eichstätt | 28 | 12 | 4 | 12 | 42:51 | -9 | 40 |
| 9 |
|
TSV Buchbach | 28 | 10 | 8 | 10 | 37:32 | 5 | 38 |
| 10 |
|
Augsburgo II | 28 | 10 | 7 | 11 | 44:50 | -6 | 37 |
| 11 |
|
1. FC Nürnberg II | 28 | 8 | 11 | 9 | 39:41 | -2 | 35 |
| 12 |
|
Viktoria Aschaffenburg | 28 | 10 | 5 | 13 | 37:42 | -5 | 35 |
| 13 |
|
FC Pipinsried | 28 | 10 | 4 | 14 | 36:53 | -17 | 34 |
| 14 |
|
SC Eltersdorf | 28 | 9 | 3 | 16 | 44:66 | -22 | 30 |
| 15 |
|
FC Memmingen | 28 | 7 | 8 | 13 | 38:58 | -20 | 29 |
| 16 |
|
SV Heimstetten | 28 | 8 | 4 | 16 | 41:57 | -16 | 28 |
| 17 |
|
TSV 1896 Rain | 28 | 8 | 4 | 16 | 25:56 | -31 | 28 |
| 18 |
|
SV Schalding-Heining | 28 | 7 | 6 | 15 | 31:48 | -17 | 27 |
| 19 |
|
SpVgg Greuther Fürth II | 28 | 5 | 9 | 14 | 34:58 | -24 | 24 |
| 20 |
|
TSV 1860 Rosenheim | 28 | 3 | 9 | 16 | 25:73 | -48 | 18 |
| Ascenso | |
| Permanencia | |
| Descenso |
