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| 13.03.2021 | 14:00 | Bor. Mönchengladbach II | - | Sportfreunde Lotte | 3:3 (1:2) | |
| 14:00 | Schalke II | - | Alemannia Aachen | 2:2 (2:1) | ||
| 14:00 | Fortuna Düsseldorf II | - | Bonner SC | 1:1 (0:1) | ||
| 14:00 | Fortuna Köln | - | SC Wiedenbrück | 0:2 (0:0) | ||
| 14:00 | Preußen Münster | - | Rot-Weiss Essen | 1:0 (0:0) | ||
| 14:00 | Rot Weiss Ahlen | - | Borussia Dortmund II | 1:1 (0:0) | ||
| 14:00 | Rot-Weiß Oberhausen | - | Colonia | 3:2 (1:1) | ||
| 14:00 | SV Rödinghausen | - | Wuppertaler SV | 1:1 (0:0) | ||
| 14:00 | SV 19 Straelen | - | FC Wegberg-Beeck | 0:0 (0:0) | ||
| 14:15 | SV Bergisch Gladbach 09 | - | VfB Homberg | 0:2 (0:2) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta | 1.ª parte | 2.ª parte |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Borussia Dortmund II | 28 | 19 | 8 | 1 | 71:21 | 50 | 65 |
| 2 |
|
Rot-Weiss Essen | 28 | 18 | 7 | 3 | 57:19 | 38 | 61 |
| 3 |
|
Preußen Münster | 29 | 18 | 5 | 6 | 46:24 | 22 | 59 |
| 4 |
|
Fortuna Düsseldorf II | 29 | 15 | 7 | 7 | 57:30 | 27 | 52 |
| 5 |
|
Fortuna Köln | 29 | 13 | 10 | 6 | 50:34 | 16 | 49 |
| 6 |
|
Rot-Weiß Oberhausen | 29 | 12 | 10 | 7 | 48:36 | 12 | 46 |
| 7 |
|
SV Rödinghausen | 29 | 12 | 8 | 9 | 38:31 | 7 | 44 |
| 8 |
|
Bor. Mönchengladbach II | 29 | 12 | 6 | 11 | 40:38 | 2 | 42 |
| 9 |
|
Colonia | 28 | 11 | 8 | 9 | 44:37 | 7 | 41 |
| 10 |
|
Schalke II | 29 | 9 | 11 | 9 | 33:32 | 1 | 38 |
| 11 |
|
SV 19 Straelen | 29 | 10 | 8 | 11 | 33:41 | -8 | 38 |
| 12 |
|
SC Wiedenbrück | 28 | 8 | 13 | 7 | 36:36 | 0 | 37 |
| 13 |
|
Alemannia Aachen | 29 | 9 | 9 | 11 | 27:33 | -6 | 36 |
| 14 |
|
Wuppertaler SV | 29 | 9 | 5 | 15 | 32:49 | -17 | 32 |
| 15 |
|
VfB Homberg | 29 | 8 | 5 | 16 | 28:49 | -21 | 29 |
| 16 |
|
FC Wegberg-Beeck | 28 | 6 | 9 | 13 | 25:42 | -17 | 27 |
| 17 |
|
SV Lippstadt 08 | 28 | 5 | 11 | 12 | 28:47 | -19 | 26 |
| 18 |
|
SV Bergisch Gladbach 09 | 29 | 6 | 7 | 16 | 27:50 | -23 | 25 |
| 19 |
|
Sportfreunde Lotte | 28 | 5 | 10 | 13 | 28:54 | -26 | 25 |
| 20 |
|
Bonner SC | 28 | 5 | 6 | 17 | 26:51 | -25 | 21 |
| 21 |
|
Rot Weiss Ahlen | 28 | 3 | 11 | 14 | 30:50 | -20 | 20 |
| Ascenso | |
| Descenso |
