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| 20.02.2021 | 13:00 | FK Mariupol | - | Zorya Lugansk | 0:1 (0:1) | |
| 16:00 | FK Oleksandriya | - | FC Mynai | 3:0 (1:0) | ||
| 18:30 | FK Lviv | - | Kolos Kovalivka | 0:2 (0:1) | ||
| 21.02.2021 | 13:00 | Inhulets Petrove | - | Vorskla Poltava | 2:2 (1:0) | |
| 16:00 | Shakhtar Donetsk | - | Rukh Lviv | 2:0 (1:0) | ||
| 18:30 | Desna Chernigov | - | Dinamo Kiev | 1:1 (0:0) | ||
| 22.02.2021 | 18:00 | Olimpik Donetsk | - | SK Dnipro-1 | 0:2 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Dinamo Kiev | 15 | 10 | 4 | 1 | 29:12 | 17 | 34 |
| 2 |
|
Shakhtar Donetsk | 15 | 9 | 6 | 0 | 35:11 | 24 | 33 |
| 3 |
|
Zorya Lugansk | 15 | 7 | 5 | 3 | 27:13 | 14 | 26 |
| 4 |
|
Desna Chernigov | 15 | 6 | 6 | 3 | 20:14 | 6 | 24 |
| 5 |
|
Vorskla Poltava | 15 | 5 | 7 | 3 | 20:13 | 7 | 22 |
| 6 |
|
Kolos Kovalivka | 15 | 5 | 7 | 3 | 20:16 | 4 | 22 |
| 7 |
|
FK Oleksandriya | 15 | 6 | 4 | 5 | 23:18 | 5 | 22 |
| 8 |
|
Olimpik Donetsk | 15 | 6 | 2 | 7 | 23:26 | -3 | 20 |
| 9 |
|
FK Mariupol | 15 | 4 | 4 | 7 | 14:21 | -7 | 16 |
| 10 |
|
FK Lviv | 15 | 4 | 3 | 8 | 11:29 | -18 | 15 |
| 11 |
|
SK Dnipro-1 | 15 | 4 | 2 | 9 | 20:28 | -8 | 14 |
| 12 |
|
Inhulets Petrove | 15 | 1 | 9 | 5 | 15:24 | -9 | 12 |
| 13 |
|
Rukh Lviv | 15 | 1 | 7 | 7 | 13:26 | -13 | 10 |
| 14 |
|
FC Mynai | 15 | 2 | 4 | 9 | 10:29 | -19 | 10 |
| Champions League | |
| CL Ronda previa | |
| ECL Ronda previa | |
| Descenso |
