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| 16.04.2021 | 16:00 | FK Lviv | - | FK Oleksandriya | 3:1 (2:1) | |
| 17.04.2021 | 13:00 | FC Mynai | - | Desna Chernigov | 3:1 (2:0) | |
| 16:00 | Vorskla Poltava | - | Zorya Lugansk | 4:2 (3:0) | ||
| 18:30 | Shakhtar Donetsk | - | Dinamo Kiev | 0:1 (0:1) | ||
| 18.04.2021 | 13:00 | Inhulets Petrove | - | Rukh Lviv | 0:0 (0:0) | |
| 16:00 | FK Mariupol | - | Olimpik Donetsk | 1:1 (1:1) | ||
| 18:30 | Kolos Kovalivka | - | SK Dnipro-1 | 1:1 (1:1) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Dinamo Kiev | 22 | 17 | 4 | 1 | 46:14 | 32 | 55 |
| 2 |
|
Shakhtar Donetsk | 22 | 13 | 6 | 3 | 47:16 | 31 | 45 |
| 3 |
|
Zorya Lugansk | 22 | 11 | 5 | 6 | 38:20 | 18 | 38 |
| 4 |
|
Vorskla Poltava | 22 | 10 | 7 | 5 | 33:20 | 13 | 37 |
| 5 |
|
Desna Chernigov | 22 | 10 | 6 | 6 | 34:24 | 10 | 36 |
| 6 |
|
Kolos Kovalivka | 22 | 8 | 10 | 4 | 29:21 | 8 | 34 |
| 7 |
|
SK Dnipro-1 | 22 | 7 | 5 | 10 | 31:34 | -3 | 26 |
| 8 |
|
FK Oleksandriya | 22 | 7 | 5 | 10 | 29:31 | -2 | 26 |
| 9 |
|
FK Mariupol | 22 | 5 | 7 | 10 | 22:35 | -13 | 22 |
| 10 |
|
FK Lviv | 22 | 6 | 4 | 12 | 21:48 | -27 | 22 |
| 11 |
|
Olimpik Donetsk | 22 | 6 | 3 | 13 | 26:39 | -13 | 21 |
| 12 |
|
Inhulets Petrove | 22 | 3 | 11 | 8 | 20:33 | -13 | 20 |
| 13 |
|
Rukh Lviv | 22 | 3 | 9 | 10 | 18:37 | -19 | 18 |
| 14 |
|
FC Mynai | 22 | 4 | 6 | 12 | 15:37 | -22 | 18 |
| Champions League | |
| CL Ronda previa | |
| ECL Ronda previa | |
| Descenso |
