 |
 |
|
|
| 13.11.2021 | 13:45 | Liverpool | - | Montevideo City Torque | 1:3 (0:1) | |
| 20:30 | Deportivo Maldonado | - | Nacional | 1:0 (0:0) | ||
| 22:45 | Cerrito | - | Villa Española | 1:0 (1:0) | ||
| 14.11.2021 | 13:45 | Sud América | - | Boston River | 1:2 (0:0) | |
| 20:30 | River Plate | - | Peñarol | 1:1 (1:0) | ||
| 22:45 | Plaza Colonia | - | Fénix | 1:1 (1:0) | ||
| 15.11.2021 | 13:45 | Cerro Largo | - | Rentistas | 1:1 (1:0) | |
| 20:30 | Progreso | - | Montevideo Wanderers | 3:1 (2:1) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Peñarol | 12 | 8 | 3 | 1 | 22:8 | 14 | 27 |
| 2 |
|
Nacional | 12 | 7 | 2 | 3 | 18:10 | 8 | 25 |
| 3 |
|
Cerro Largo | 12 | 6 | 5 | 1 | 19:9 | 10 | 22 |
| 4 |
|
Progreso | 12 | 6 | 3 | 3 | 11:6 | 5 | 21 |
| 5 |
|
Montevideo City Torque | 12 | 6 | 2 | 4 | 23:17 | 6 | 20 |
| 6 |
|
Montevideo Wanderers | 12 | 6 | 2 | 4 | 17:16 | 1 | 20 |
| 7 |
|
Plaza Colonia | 12 | 4 | 5 | 3 | 17:13 | 4 | 17 |
| 8 |
|
Deportivo Maldonado | 12 | 5 | 2 | 5 | 11:13 | -2 | 17 |
| 9 |
|
Cerrito | 12 | 4 | 3 | 5 | 17:20 | -3 | 15 |
| 10 |
|
Boston River | 12 | 4 | 3 | 5 | 20:24 | -4 | 15 |
| 11 |
|
Fénix | 12 | 3 | 5 | 4 | 15:16 | -1 | 14 |
| 12 |
|
Rentistas | 12 | 4 | 2 | 6 | 15:17 | -2 | 14 |
| 13 |
|
River Plate | 12 | 3 | 3 | 6 | 11:15 | -4 | 12 |
| 14 |
|
Liverpool | 12 | 3 | 2 | 7 | 9:15 | -6 | 11 |
| 15 |
|
Sud América | 12 | 2 | 4 | 6 | 9:18 | -9 | 10 |
| 16 |
|
Villa Española | 12 | 1 | 2 | 9 | 9:26 | -17 | 5 |
| Playoff |
