| 1. Jornada | 22.08.2021 | Olympiacos Nikosia | - | Aris Limassol | 1:2 | ||||
| 2. Jornada | 13.09.2021 | APOEL Nikosia | - | Olympiacos Nikosia | 0:1 | ||||
| 4. Jornada | 27.09.2021 | AEK Larnaca | - | Olympiacos Nikosia | 1:0 |  |
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| 5. Jornada | 03.10.2021 | Olympiacos Nikosia | - | Omonia Nikosia | 1:0 | ||||
| 10. Jornada | 20.11.2021 | Olympiacos Nikosia | - | Anorthosis Famagusta | 3:2 | ||||
| 11. Jornada | 26.11.2021 | Ethnikos Achna | - | Olympiacos Nikosia | 1:0 | |
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| 12. Jornada | 03.12.2021 | Aris Limassol | - | Olympiacos Nikosia | 1:0 | ||||
| 13. Jornada | 12.12.2021 | Olympiacos Nikosia | - | APOEL Nikosia | 1:1 | |
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| 14. Jornada | 19.12.2021 | AEL Limassol | - | Olympiacos Nikosia | 3:0 | ||||
| 16. Jornada | 10.01.2022 | Omonia Nikosia | - | Olympiacos Nikosia | 1:0 | ||||
| 17. Jornada | 15.01.2022 | Olympiacos Nikosia | - | Paphos FC | 1:2 | ||||
| 18. Jornada | 23.01.2022 | Doxa Katokopias | - | Olympiacos Nikosia | 0:0 | ||||
| 19. Jornada | 30.01.2022 | Apollon Limassol | - | Olympiacos Nikosia | 2:1 | ||||
| 21. Jornada | 14.02.2022 | Anorthosis Famagusta | - | Olympiacos Nikosia | 3:1 | ||||
| 20. Jornada | 22.02.2022 | Olympiacos Nikosia | - | PAEEK | 1:0 | |
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| 22. Jornada | 27.02.2022 | Olympiacos Nikosia | - | Ethnikos Achna | 0:0 |
Francia