| 1. Jornada | 09.07.2016 | Libertad | - | River Plate | 1:1 |  |
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| 2. Jornada | 17.07.2016 | River Plate | - | General Díaz | 0:0 | ||||
| 3. Jornada | 20.07.2016 | Guaraní | - | River Plate | 2:0 | ||||
| 4. Jornada | 25.07.2016 | River Plate | - | Club Olimpia | 0:2 | |
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| 5. Jornada | 02.08.2016 | Club Rubio Ñu | - | River Plate | 5:1 | |
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| 6. Jornada | 07.08.2016 | River Plate | - | General Caballero ZC | 1:1 | |
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| 7. Jornada | 12.08.2016 | Sportivo Luqueño | - | River Plate | 1:0 | |
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| 10. Jornada | 10.09.2016 | Sol de América | - | River Plate | 2:6 |  |
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| 11. Jornada | 18.09.2016 | River Plate | - | Club Nacional | 2:3 | |
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| 12. Jornada | 24.09.2016 | River Plate | - | Libertad | 2:0 | ||||
| 13. Jornada | 30.09.2016 | General Díaz | - | River Plate | 2:0 | |
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| 14. Jornada | 17.10.2016 | River Plate | - | Guaraní | 0:2 | ||||
| 15. Jornada | 23.10.2016 | Club Olimpia | - | River Plate | 5:3 | |
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| 16. Jornada | 29.10.2016 | River Plate | - | Club Rubio Ñu | 0:2 |  |
Paraguay