Plan de juego
| Fecha | Ronda | Partido | Partido | Res. | Espectadores | |
|---|---|---|---|---|---|---|
| 03.02.2018 |  | 1. Jornada | River Plate - Boston River | Riv - Bos | 2:2 | |
| 18.02.2018 | | 3. Jornada | River Plate - Atenas | Riv - Ate | 3:1 | |
| 04.03.2018 | | 5. Jornada | River Plate - Torque | Riv - MCT | 2:2 | |
| 17.03.2018 | | 7. Jornada | River Plate - Fénix | Riv - Fén | 2:1 | |
| 28.03.2018 | | 9. Jornada | River Plate - Progreso | Riv - Pro | 4:2 | |
| 08.04.2018 | | 11. Jornada | River Plate - Racing | Riv - Rac | 1:1 | |
| 14.04.2018 | | 12. Jornada | River Plate - CA Cerro | Riv - CA | 1:1 | |
| 29.04.2018 | | 14. Jornada | River Plate - Liverpool FC | Riv - LFC | 5:0 | |
| 12.05.2018 | | 2. Jornada | River Plate - Defensor | Riv - Def | 1:0 | |
| 30.05.2018 | | 5. Jornada | River Plate - Boston River | Riv - Bos | 1:0 | |
| 29.07.2018 | | 2. Jornada | River Plate - Peñarol | Riv - PEN | 0:1 | |
| 12.08.2018 | | 4. Jornada | River Plate - Danubio | Riv - Dan | 1:2 | |
| 26.08.2018 | | 6. Jornada | River Plate - Rampla Juniors | Riv - Ram | 3:4 | |
| 09.09.2018 | | 8. Jornada | River Plate - Nacional | Riv - Nac | 0:0 | |
| 23.09.2018 | | 10. Jornada | River Plate - Defensor | Riv - Def | 3:2 | |
| 21.10.2018 | | 13. Jornada | River Plate - Wanderers | Riv - MWF | 0:5 | |
| 04.11.2018 | | 15. Jornada | Nacional - Danubio | Nac - Dan | 1:0 |