Plan de juego
| Fecha | Ronda | Partido | Partido | Res. | Espectadores | |
|---|---|---|---|---|---|---|
| 27.01.2021 |  | 4. Jornada | Chania - Ergotelis | CFC - Erg | 0:1 | |
| 03.02.2021 | | 1. Jornada | Chania - Doxa Dramas FC | CFC - | 1:0 | |
| 07.02.2021 | | 6. Jornada | Chania - Trikala | CFC - | 1:2 | |
| 13.02.2021 | | 8. Jornada | Chania - OFI Ierapetra | CFC - | 1:0 | |
| 17.02.2021 | | 9. Jornada | Chania - Panachaiki GE | CFC - Pan | 0:0 | |
| 27.02.2021 | | 11. Jornada | Chania - Ionikos | CFC - Ion | 0:1 | |
| 07.03.2021 | | 13. Jornada | Chania - Levadiakos | CFC - Lev | 0:0 | |
| 13.03.2021 | | 14. Jornada | Chania - Karaiskakis | CFC - | 1:0 | |
| 21.03.2021 | | 16. Jornada | Chania - Xhanti FC | CFC - Xan | 0:0 | |
| 03.04.2021 | | 18. Jornada | Chania - Diagoras FC | CFC - DFC | 1:0 | |
| 18.04.2021 | | 21. Jornada | Chania - Apollon Lárissa | CFC - | 2:1 | |
| 05.05.2021 | | 2. Jornada | Chania - Ionikos | CFC - Ion | 1:0 | |
| 19.05.2021 | | 5. Jornada | Chania - Diagoras FC | CFC - DFC | 2:0 | |
| 25.09.2021 |  | Tercera ronda | Aris Soudas - Diagoras FC | - DFC | 0:1 | |
| 24.11.2021 | | 4. Jornada | Chania - AS Rhodos | CFC - | 2:2 | |
| 05.12.2021 | | 6. Jornada | Chania - AE Kifisias | CFC - | 3:0 | |
| 15.12.2021 | | 8. Jornada | Chania - Kalamata | CFC - | 1:2 | |
| 29.12.2021 | | 10. Jornada | Chania - Karaiskakis | CFC - | 4:0 |