Entradas
| a partir de | Apellido | Pos | Equipo | Equipo | ||
|---|---|---|---|---|---|---|
| 12/2021 |  | Carlos Anguiano | M |  | Tacoma Defiance | Tacoma Def. |
| 12/2021 |  | Baboucarr Njie | M |  | Rio Grande Valley FC | RGV FC |
| 12/2021 | | Marcus Epps | M |  | San Antonio FC | San Antonio FC |
| 09/2021 |  | Jonathan Levin | M | |||
| 09/2021 | | David Loera | M |  | Orlando City | Orlando City |
| 09/2021 |  | Luis Seijas | M | |||
| 08/2021 |  | Darren Mattocks | A | |||
| 07/2021 | | Manuel Madrid | D |  | Mineros de Zacatecas | Zacatecas |
| 06/2021 | | Tate Schmitt | M |  | Real Salt Lake | Salt Lake |
| 06/2021 |  | David Egbo | A |  | Vancouver Whitecaps | Vancouver |
| 05/2021 |  | Ben Lundt | P |  | FC Cincinnati | Cincinnati |
| 04/2021 | | Niall Dunn | D | |||
| 04/2021 |  | Noah Billingsley | D |  | Minnesota United FC | Minnesota Utd |
| 03/2021 | | Ryan Flood | A | |||
| 03/2021 | | Andre Rawls | P |  | Colorado Rapids | Colorado Rapids |
| 03/2021 | | Jeremy Kelly | M | | Colorado Rapids | Colorado Rapids |
| 03/2021 |  | Danny Stone | As |  | OKC Energy FC | OKC Energy |
| 03/2021 | | James Musa | M | |||
| 01/2021 | | Deklan Wynne | D | | Colorado Rapids | Colorado Rapids |
| 01/2021 |  | Prince Saydee | A |  | Miami FC | Miami FC |
| 01/2021 | | Edward Delgado | P |  | Las Vegas Lights FC | Las Vegas Lights FC |
| 01/2021 | | Seyi Adekoya | A |
Salidas
| a partir de | Apellido | Pos | Equipo | Equipo | ||
|---|---|---|---|---|---|---|
| 12/2021 | | David Loera | M | | Orlando City | Orlando City |
| 12/2021 | | Tate Schmitt | M | | Real Salt Lake | Salt Lake |
| 12/2021 | | David Egbo | A | | Vancouver Whitecaps | Vancouver |
| 09/2021 | | Tobi Adewole | D |  | Indy Eleven | Indy Eleven |
| 08/2021 | | Ben Lundt | P | | FC Cincinnati | Cincinnati |
| 08/2021 |  | Rufat Dadashov | A |  | FC Schalke 04 II | Schalke II |
| 08/2021 | | Seyi Adekoya | A | | OKC Energy FC | OKC Energy |
| 07/2021 | | Deklan Wynne | D | | OKC Energy FC | OKC Energy |
| 07/2021 | | Jeremy Kelly | M | | Colorado Rapids | Colorado Rapids |
| 02/2021 | | A.J. Cochran | D | | Indy Eleven | Indy Eleven |
| 01/2021 |  | Corey Whelan | D |  | Wigan Athletic | Wigan |
| 01/2021 | | Junior Flemmings | M |  | Birmingham Legion | Legion FC |
| 01/2021 |  | Jose Aguinaga | A |  | El Paso Locomotive | El Paso |