22. Jornada
01.07.2022 23:00
02.07.2022 01:15
02.07.2022 23:00
03.07.2022 01:15
03.07.2022 22:00
04.07.2022 00:15
| # | Team | Team | Pun. | V | E | D | Goles | DG | P. | ||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Libertad | Libertad | 22 | 18 | 3 | 1 | 49:14 | 35 | 57 | |
| 2 |  | Cerro Porteño | Cerro Porteño | 22 | 16 | 2 | 4 | 38:13 | 25 | 50 | |
| 3 |  | Club Olimpia | Olimpia | 22 | 13 | 4 | 5 | 41:23 | 18 | 43 | |
| 4 |  | Guaraní | Club Guaraní | 22 | 9 | 5 | 8 | 30:24 | 6 | 32 | |
| 5 |  | Resistencia SC | Resistencia | 22 | 7 | 7 | 8 | 30:36 | -6 | 28 | |
| 6 |  | Club Nacional | Nacional | 22 | 7 | 5 | 10 | 27:32 | -5 | 26 | |
| 7 |  | Sol de América | Sol de América | 22 | 6 | 7 | 9 | 20:28 | -8 | 25 | |
| 8 |  | Guaireña FC | Guaireña | 22 | 5 | 8 | 9 | 21:26 | -5 | 23 | |
| 9 |  | General Caballero JLM | Caballero | 22 | 6 | 5 | 11 | 23:33 | -10 | 23 | |
| 10 |  | Tacuary | Tacuary | 22 | 6 | 4 | 12 | 16:29 | -13 | 22 | |
| 11 |  | Sportivo Ameliano | Ameliano | 22 | 5 | 4 | 13 | 25:38 | -13 | 19 | |
| 12 |  | 12 de Octubre de Itauguá | 12 de Octubre | 22 | 3 | 8 | 11 | 16:40 | -24 | 17 |
- Copa Libertadores
| # | Team | Team | Pun. | V | E | D | Goles | DG | P. | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | | Libertad | Libertad | 11 | 10 | 1 | 0 | 22:3 | 19 | 31 |
| 2 | | Cerro Porteño | Cerro Porteño | 11 | 9 | 1 | 1 | 21:5 | 16 | 28 |
| 3 | | Club Olimpia | Olimpia | 11 | 6 | 2 | 3 | 20:14 | 6 | 20 |
| 4 | | Resistencia SC | Resistencia | 11 | 5 | 2 | 4 | 14:15 | -1 | 17 |
| 5 | | Tacuary | Tacuary | 11 | 4 | 3 | 4 | 12:13 | -1 | 15 |
| 6 | | Sol de América | Sol de América | 11 | 3 | 4 | 4 | 9:12 | -3 | 13 |
| 7 | | Guaraní | Club Guaraní | 11 | 3 | 3 | 5 | 15:15 | 0 | 12 |
| 8 | | Club Nacional | Nacional | 11 | 3 | 2 | 6 | 15:19 | -4 | 11 |
| 9 | | Guaireña FC | Guaireña | 11 | 2 | 5 | 4 | 9:13 | -4 | 11 |
| 10 | | General Caballero JLM | Caballero | 11 | 2 | 3 | 6 | 8:16 | -8 | 9 |
| 11 | | Sportivo Ameliano | Ameliano | 11 | 2 | 3 | 6 | 13:22 | -9 | 9 |
| 12 | | 12 de Octubre de Itauguá | 12 de Octubre | 11 | 2 | 2 | 7 | 9:22 | -13 | 8 |
- Copa Libertadores
| # | Team | Team | Pun. | V | E | D | Goles | DG | P. | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | | Libertad | Libertad | 11 | 8 | 2 | 1 | 27:11 | 16 | 26 |
| 2 | | Club Olimpia | Olimpia | 11 | 7 | 2 | 2 | 21:9 | 12 | 23 |
| 3 | | Cerro Porteño | Cerro Porteño | 11 | 7 | 1 | 3 | 17:8 | 9 | 22 |
| 4 | | Guaraní | Club Guaraní | 11 | 6 | 2 | 3 | 15:9 | 6 | 20 |
| 5 | | Club Nacional | Nacional | 11 | 4 | 3 | 4 | 12:13 | -1 | 15 |
| 6 | | General Caballero JLM | Caballero | 11 | 4 | 2 | 5 | 15:17 | -2 | 14 |
| 7 | | Guaireña FC | Guaireña | 11 | 3 | 3 | 5 | 12:13 | -1 | 12 |
| 8 | | Sol de América | Sol de América | 11 | 3 | 3 | 5 | 11:16 | -5 | 12 |
| 9 | | Resistencia SC | Resistencia | 11 | 2 | 5 | 4 | 16:21 | -5 | 11 |
| 10 | | Sportivo Ameliano | Ameliano | 11 | 3 | 1 | 7 | 12:16 | -4 | 10 |
| 11 | | 12 de Octubre de Itauguá | 12 de Octubre | 11 | 1 | 6 | 4 | 7:18 | -11 | 9 |
| 12 | | Tacuary | Tacuary | 11 | 2 | 1 | 8 | 4:16 | -12 | 7 |
- Copa Libertadores
| # | Team | Team | Pun. | V | E | D | Goles | DG | P. | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | | Libertad | Libertad | 11 | 8 | 2 | 1 | 25:12 | 13 | 26 |
| 2 | | Cerro Porteño | Cerro Porteño | 11 | 8 | 1 | 2 | 23:8 | 15 | 25 |
| 3 | | Resistencia SC | Resistencia | 11 | 5 | 5 | 1 | 21:16 | 5 | 20 |
| 4 | | Club Olimpia | Olimpia | 11 | 5 | 3 | 3 | 15:11 | 4 | 18 |
| 5 | | Club Nacional | Nacional | 11 | 5 | 2 | 4 | 16:17 | -1 | 17 |
| 6 | | Sol de América | Sol de América | 11 | 4 | 2 | 5 | 9:15 | -6 | 14 |
| 7 | | Tacuary | Tacuary | 11 | 4 | 1 | 6 | 9:11 | -2 | 13 |
| 8 | | Guaireña FC | Guaireña | 11 | 3 | 3 | 5 | 10:15 | -5 | 12 |
| 9 | | Guaraní | Club Guaraní | 11 | 3 | 2 | 6 | 11:14 | -3 | 11 |
| 10 | | General Caballero JLM | Caballero | 11 | 2 | 3 | 6 | 10:14 | -4 | 9 |
| 11 | | Sportivo Ameliano | Ameliano | 11 | 3 | 0 | 8 | 12:19 | -7 | 9 |
| 12 | | 12 de Octubre de Itauguá | 12 de Octubre | 11 | 1 | 6 | 4 | 8:17 | -9 | 9 |
- Copa Libertadores
| # | Team | Team | Pun. | V | E | D | Goles | DG | P. | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | | Libertad | Libertad | 11 | 10 | 1 | 0 | 24:2 | 22 | 31 |
| 2 | | Club Olimpia | Olimpia | 11 | 8 | 1 | 2 | 26:12 | 14 | 25 |
| 3 | | Cerro Porteño | Cerro Porteño | 11 | 8 | 1 | 2 | 15:5 | 10 | 25 |
| 4 | | Guaraní | Club Guaraní | 11 | 6 | 3 | 2 | 19:10 | 9 | 21 |
| 5 | | General Caballero JLM | Caballero | 11 | 4 | 2 | 5 | 13:19 | -6 | 14 |
| 6 | | Guaireña FC | Guaireña | 11 | 2 | 5 | 4 | 11:11 | 0 | 11 |
| 7 | | Sol de América | Sol de América | 11 | 2 | 5 | 4 | 11:13 | -2 | 11 |
| 8 | | Sportivo Ameliano | Ameliano | 11 | 2 | 4 | 5 | 13:19 | -6 | 10 |
| 9 | | Club Nacional | Nacional | 11 | 2 | 3 | 6 | 11:15 | -4 | 9 |
| 10 | | Tacuary | Tacuary | 11 | 2 | 3 | 6 | 7:18 | -11 | 9 |
| 11 | | Resistencia SC | Resistencia | 11 | 2 | 2 | 7 | 9:20 | -11 | 8 |
| 12 | | 12 de Octubre de Itauguá | 12 de Octubre | 11 | 2 | 2 | 7 | 8:23 | -15 | 8 |
- Copa Libertadores