18. Jornada
20.11.2021 16:00
20.11.2021 17:00
20.11.2021 18:00
20.11.2021 18:30
20.11.2021 19:00
20.11.2021 23:00
| # | Team | Team | Pun. | V | E | D | Goles | DG | P. | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Deportivo Guadalajara | Deportivo Guadalajara | 16 | 11 | 4 | 1 | 49:17 | 32 | 37 |
| 2 |  | Deportivo Toluca | Deportivo Toluca | 16 | 10 | 5 | 1 | 30:15 | 15 | 35 |
| 3 |  | Pumas UNAM | Pumas UNAM | 16 | 10 | 3 | 3 | 27:14 | 13 | 33 |
| 4 |  | Santos Laguna | Santos Laguna | 16 | 9 | 4 | 3 | 30:19 | 11 | 31 |
| 5 |  | UANL Tigres | UANL Tigres | 16 | 8 | 4 | 4 | 29:19 | 10 | 28 |
| 6 |  | CF Pachuca | CF Pachuca | 16 | 8 | 3 | 5 | 22:20 | 2 | 27 |
| 7 |  | Cruz Azul | Cruz Azul | 16 | 7 | 4 | 5 | 18:17 | 1 | 25 |
| 8 |  | Club León | Club León | 16 | 7 | 3 | 6 | 24:21 | 3 | 24 |
| 9 |  | Club Tijuana | Club Tijuana | 16 | 7 | 3 | 6 | 20:21 | -1 | 24 |
| 10 |  | Club Necaxa | Club Necaxa | 16 | 6 | 3 | 7 | 23:19 | 4 | 21 |
| 11 |  | CF Monterrey | CF Monterrey | 16 | 5 | 5 | 6 | 22:28 | -6 | 20 |
| 12 |  | Atlas Guadalajara | Atlas FC 4a | 16 | 6 | 1 | 9 | 33:33 | 0 | 19 |
| 13 |  | Puebla FC | Puebla FC | 16 | 5 | 4 | 7 | 25:28 | -3 | 19 |
| 14 |  | Mazatlán FC | Mazatlán FC | 16 | 5 | 1 | 10 | 25:47 | -22 | 16 |
| 15 |  | Gallos Blancos | Gallos Blancos | 16 | 3 | 5 | 8 | 21:24 | -3 | 14 |
| 16 |  | CF América | CF América | 16 | 4 | 2 | 10 | 20:27 | -7 | 14 |
| 17 |  | FC Juárez | FC Juárez | 16 | 2 | 3 | 11 | 13:30 | -17 | 9 |
| 18 |  | Atlético San Luis | Atlético San Luis | 16 | 2 | 1 | 13 | 13:45 | -32 | 7 |
- Playoff
| # | Team | Team | Pun. | V | E | D | Goles | DG | P. | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | | Deportivo Toluca | Deportivo Toluca | 8 | 7 | 1 | 0 | 18:5 | 13 | 22 |
| 2 | | Pumas UNAM | Pumas UNAM | 8 | 6 | 2 | 0 | 17:5 | 12 | 20 |
| 3 | | UANL Tigres | UANL Tigres | 8 | 5 | 2 | 1 | 19:7 | 12 | 17 |
| 4 | | Club Tijuana | Club Tijuana | 8 | 5 | 2 | 1 | 13:6 | 7 | 17 |
| 5 | | Santos Laguna | Santos Laguna | 8 | 5 | 1 | 2 | 14:8 | 6 | 16 |
| 6 | | Deportivo Guadalajara | Deportivo Guadalajara | 8 | 4 | 3 | 1 | 16:8 | 8 | 15 |
| 7 | | CF Pachuca | CF Pachuca | 8 | 4 | 2 | 2 | 13:9 | 4 | 14 |
| 8 | | CF Monterrey | CF Monterrey | 8 | 4 | 2 | 2 | 17:18 | -1 | 14 |
| 9 | | Club Necaxa | Club Necaxa | 8 | 3 | 2 | 3 | 11:7 | 4 | 11 |
| 10 | | Puebla FC | Puebla FC | 8 | 3 | 2 | 3 | 16:14 | 2 | 11 |
| 11 | | Cruz Azul | Cruz Azul | 8 | 3 | 2 | 3 | 9:8 | 1 | 11 |
| 12 | | Atlas Guadalajara | Atlas FC 4a | 8 | 3 | 1 | 4 | 22:19 | 3 | 10 |
| 13 | | CF América | CF América | 8 | 3 | 1 | 4 | 12:11 | 1 | 10 |
| 14 | | Club León | Club León | 8 | 3 | 1 | 4 | 11:15 | -4 | 10 |
| 15 | | Mazatlán FC | Mazatlán FC | 8 | 3 | 1 | 4 | 11:18 | -7 | 10 |
| 16 | | Gallos Blancos | Gallos Blancos | 8 | 2 | 3 | 3 | 10:9 | 1 | 9 |
| 17 | | FC Juárez | FC Juárez | 8 | 2 | 1 | 5 | 8:13 | -5 | 7 |
| 18 | | Atlético San Luis | Atlético San Luis | 8 | 2 | 0 | 6 | 8:19 | -11 | 6 |
- Playoff
| # | Team | Team | Pun. | V | E | D | Goles | DG | P. | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | | Deportivo Guadalajara | Deportivo Guadalajara | 8 | 7 | 1 | 0 | 33:9 | 24 | 22 |
| 2 | | Santos Laguna | Santos Laguna | 8 | 4 | 3 | 1 | 16:11 | 5 | 15 |
| 3 | | Club León | Club León | 8 | 4 | 2 | 2 | 13:6 | 7 | 14 |
| 4 | | Cruz Azul | Cruz Azul | 8 | 4 | 2 | 2 | 9:9 | 0 | 14 |
| 5 | | Deportivo Toluca | Deportivo Toluca | 8 | 3 | 4 | 1 | 12:10 | 2 | 13 |
| 6 | | Pumas UNAM | Pumas UNAM | 8 | 4 | 1 | 3 | 10:9 | 1 | 13 |
| 7 | | CF Pachuca | CF Pachuca | 8 | 4 | 1 | 3 | 9:11 | -2 | 13 |
| 8 | | UANL Tigres | UANL Tigres | 8 | 3 | 2 | 3 | 10:12 | -2 | 11 |
| 9 | | Club Necaxa | Club Necaxa | 8 | 3 | 1 | 4 | 12:12 | 0 | 10 |
| 10 | | Atlas Guadalajara | Atlas FC 4a | 8 | 3 | 0 | 5 | 11:14 | -3 | 9 |
| 11 | | Puebla FC | Puebla FC | 8 | 2 | 2 | 4 | 9:14 | -5 | 8 |
| 12 | | Club Tijuana | Club Tijuana | 8 | 2 | 1 | 5 | 7:15 | -8 | 7 |
| 13 | | CF Monterrey | CF Monterrey | 8 | 1 | 3 | 4 | 5:10 | -5 | 6 |
| 14 | | Mazatlán FC | Mazatlán FC | 8 | 2 | 0 | 6 | 14:29 | -15 | 6 |
| 15 | | Gallos Blancos | Gallos Blancos | 8 | 1 | 2 | 5 | 11:15 | -4 | 5 |
| 16 | | CF América | CF América | 8 | 1 | 1 | 6 | 8:16 | -8 | 4 |
| 17 | | FC Juárez | FC Juárez | 8 | 0 | 2 | 6 | 5:17 | -12 | 2 |
| 18 | | Atlético San Luis | Atlético San Luis | 8 | 0 | 1 | 7 | 5:26 | -21 | 1 |
- Playoff