25. Jornada
07.10.2021 01:30
09.10.2021 17:30
09.10.2021 20:30
09.10.2021 23:00
10.10.2021 01:30
10.10.2021 19:00
11.10.2021 21:00
12.10.2021 01:30
| # | Team | Team | Pun. | V | E | D | Goles | DG | P. | ||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Colo-Colo | Colo-Colo | 24 | 15 | 4 | 5 | 39:20 | 19 | 49 | |
| 2 |  | Universidad Católica | U. Católica | 23 | 14 | 2 | 7 | 43:28 | 15 | 44 | |
| 3 |  | Audax Italiano | Audax Italiano | 24 | 11 | 8 | 5 | 31:24 | 7 | 41 | |
| 4 |  | Unión La Calera | La Calera | 23 | 12 | 5 | 6 | 28:25 | 3 | 41 | |
| 5 |  | Unión Española | Unión Española | 24 | 11 | 3 | 10 | 38:35 | 3 | 36 | |
| 6 |  | Universidad de Chile | Uni. de Chile | 23 | 9 | 7 | 7 | 30:26 | 4 | 34 | |
| 7 |  | Everton | Everton | 23 | 9 | 7 | 7 | 20:19 | 1 | 34 | |
| 8 |  | Cobresal | CD Cobresal | 24 | 9 | 5 | 10 | 30:26 | 4 | 32 | |
| 9 |  | Antofagasta | Antofagasta | 23 | 8 | 8 | 7 | 28:29 | -1 | 32 | |
| 10 |  | La Serena | La Serena | 24 | 8 | 7 | 9 | 31:29 | 2 | 31 | |
| 11 |  | Ñublense | Ñublense | 24 | 7 | 9 | 8 | 32:29 | 3 | 30 | |
| 12 |  | Palestino | Palestino | 23 | 8 | 4 | 11 | 33:35 | -2 | 28 | |
| 13 |  | O'Higgins | O'Higgins | 24 | 7 | 7 | 10 | 21:31 | -10 | 28 | |
| 14 |  | Curicó Unido | Curicó Unido | 24 | 6 | 9 | 9 | 28:31 | -3 | 27 | |
| 15 |  | Huachipato | Huachipato | 23 | 4 | 11 | 8 | 26:34 | -8 | 23 | |
| 16 |  | Deportes Melipilla | Dep. Melipilla | 24 | 5 | 7 | 12 | 26:42 | -16 | 22 | |
| 17 |  | Santiago Wanderers | Wanderers | 23 | 4 | 3 | 16 | 17:38 | -21 | 15 |
- Copa Libertadores
- Clasificación
- Copa Sudamericana
- Relegation
- Descenso
| # | Team | Team | Pun. | V | E | D | Goles | DG | P. | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | | Universidad Católica | U. Católica | 12 | 10 | 2 | 0 | 29:10 | 19 | 32 |
| 2 | | Cobresal | CD Cobresal | 12 | 7 | 2 | 3 | 21:10 | 11 | 23 |
| 3 | | Unión Española | Unión Española | 12 | 7 | 2 | 3 | 23:18 | 5 | 23 |
| 4 | | Audax Italiano | Audax Italiano | 12 | 7 | 2 | 3 | 17:13 | 4 | 23 |
| 5 | | Unión La Calera | La Calera | 12 | 7 | 2 | 3 | 13:11 | 2 | 23 |
| 6 | | Antofagasta | Antofagasta | 12 | 7 | 1 | 4 | 16:14 | 2 | 22 |
| 7 | | La Serena | La Serena | 12 | 6 | 3 | 3 | 18:12 | 6 | 21 |
| 8 | | Colo-Colo | Colo-Colo | 12 | 6 | 2 | 4 | 14:7 | 7 | 20 |
| 9 | | Ñublense | Ñublense | 12 | 5 | 4 | 3 | 19:10 | 9 | 19 |
| 10 | | Everton | Everton | 12 | 5 | 4 | 3 | 11:10 | 1 | 19 |
| 11 | | O'Higgins | O'Higgins | 12 | 5 | 4 | 3 | 13:13 | 0 | 19 |
| 12 | | Palestino | Palestino | 11 | 5 | 2 | 4 | 17:14 | 3 | 17 |
| 13 | | Curicó Unido | Curicó Unido | 12 | 4 | 5 | 3 | 17:15 | 2 | 17 |
| 14 | | Universidad de Chile | Uni. de Chile | 11 | 4 | 4 | 3 | 13:13 | 0 | 16 |
| 15 | | Deportes Melipilla | Dep. Melipilla | 12 | 2 | 6 | 4 | 16:19 | -3 | 12 |
| 16 | | Huachipato | Huachipato | 11 | 2 | 6 | 3 | 10:13 | -3 | 12 |
| 17 | | Santiago Wanderers | Wanderers | 11 | 2 | 2 | 7 | 10:22 | -12 | 8 |
- Copa Libertadores
- Clasificación
- Copa Sudamericana
- Relegation
- Descenso
| # | Team | Team | Pun. | V | E | D | Goles | DG | P. | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | | Colo-Colo | Colo-Colo | 12 | 9 | 2 | 1 | 25:13 | 12 | 29 |
| 2 | | Universidad de Chile | Uni. de Chile | 12 | 5 | 3 | 4 | 17:13 | 4 | 18 |
| 3 | | Audax Italiano | Audax Italiano | 12 | 4 | 6 | 2 | 14:11 | 3 | 18 |
| 4 | | Unión La Calera | La Calera | 11 | 5 | 3 | 3 | 15:14 | 1 | 18 |
| 5 | | Everton | Everton | 11 | 4 | 3 | 4 | 9:9 | 0 | 15 |
| 6 | | Unión Española | Unión Española | 12 | 4 | 1 | 7 | 15:17 | -2 | 13 |
| 7 | | Universidad Católica | U. Católica | 11 | 4 | 0 | 7 | 14:18 | -4 | 12 |
| 8 | | Huachipato | Huachipato | 12 | 2 | 5 | 5 | 16:21 | -5 | 11 |
| Palestino | Palestino | 12 | 3 | 2 | 7 | 16:21 | -5 | 11 | |
| 10 | | Ñublense | Ñublense | 12 | 2 | 5 | 5 | 13:19 | -6 | 11 |
| 11 | | Antofagasta | Antofagasta | 11 | 1 | 7 | 3 | 12:15 | -3 | 10 |
| 12 | | La Serena | La Serena | 12 | 2 | 4 | 6 | 13:17 | -4 | 10 |
| 13 | | Curicó Unido | Curicó Unido | 12 | 2 | 4 | 6 | 11:16 | -5 | 10 |
| 14 | | Deportes Melipilla | Dep. Melipilla | 12 | 3 | 1 | 8 | 10:23 | -13 | 10 |
| 15 | | Cobresal | CD Cobresal | 12 | 2 | 3 | 7 | 9:16 | -7 | 9 |
| 16 | | O'Higgins | O'Higgins | 12 | 2 | 3 | 7 | 8:18 | -10 | 9 |
| 17 | | Santiago Wanderers | Wanderers | 12 | 2 | 1 | 9 | 7:16 | -9 | 7 |
- Copa Libertadores
- Clasificación
- Copa Sudamericana
- Relegation
- Descenso