28. Jornada
23.10.2021 23:00
24.10.2021 17:00
24.10.2021 21:30
25.10.2021 01:00
25.10.2021 17:30
25.10.2021 21:00
26.10.2021 02:00
26.10.2021 16:00
| # | Team | Team | Pun. | V | E | D | Goles | DG | P. | ||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Colo-Colo | Colo-Colo | 26 | 17 | 4 | 5 | 45:22 | 23 | 55 | |
| 2 |  | Universidad Católica | U. Católica | 26 | 16 | 2 | 8 | 50:33 | 17 | 50 | |
| 3 |  | Audax Italiano | Audax Italiano | 27 | 12 | 9 | 6 | 32:27 | 5 | 45 | |
| 4 |  | Unión La Calera | La Calera | 26 | 13 | 6 | 7 | 32:28 | 4 | 45 | |
| 5 |  | Unión Española | Unión Española | 26 | 13 | 3 | 10 | 42:37 | 5 | 42 | |
| 6 |  | Everton | Everton | 26 | 10 | 8 | 8 | 23:22 | 1 | 38 | |
| 7 |  | Antofagasta | Antofagasta | 26 | 10 | 8 | 8 | 31:31 | 0 | 38 | |
| 8 |  | Cobresal | CD Cobresal | 27 | 10 | 5 | 12 | 35:33 | 2 | 35 | |
| 9 |  | Ñublense | Ñublense | 27 | 8 | 10 | 9 | 36:32 | 4 | 34 | |
| 10 |  | Universidad de Chile | Uni. de Chile | 26 | 9 | 7 | 10 | 30:31 | -1 | 34 | |
| 11 |  | Palestino | Palestino | 26 | 9 | 6 | 11 | 39:40 | -1 | 33 | |
| 12 |  | La Serena | La Serena | 27 | 8 | 9 | 10 | 36:37 | -1 | 33 | |
| 13 |  | O'Higgins | O'Higgins | 27 | 8 | 8 | 11 | 27:37 | -10 | 32 | |
| 14 |  | Deportes Melipilla | Dep. Melipilla | 27 | 7 | 8 | 12 | 32:44 | -12 | 29 | |
| 15 |  | Curicó Unido | Curicó Unido | 26 | 6 | 10 | 10 | 30:34 | -4 | 28 | |
| 16 |  | Huachipato | Huachipato | 26 | 4 | 12 | 10 | 26:36 | -10 | 24 | |
| 17 |  | Santiago Wanderers | Wanderers | 26 | 5 | 3 | 18 | 21:43 | -22 | 18 |
- Copa Libertadores
- Clasificación
- Copa Sudamericana
- Relegation
- Descenso
| # | Team | Team | Pun. | V | E | D | Goles | DG | P. | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | | Universidad Católica | U. Católica | 13 | 11 | 2 | 0 | 32:12 | 20 | 35 |
| 2 | | Unión Española | Unión Española | 13 | 8 | 2 | 3 | 25:19 | 6 | 26 |
| 3 | | Cobresal | CD Cobresal | 14 | 7 | 2 | 5 | 24:16 | 8 | 23 |
| 4 | | Colo-Colo | Colo-Colo | 13 | 7 | 2 | 4 | 16:8 | 8 | 23 |
| 5 | | Audax Italiano | Audax Italiano | 13 | 7 | 2 | 4 | 17:16 | 1 | 23 |
| 6 | | Unión La Calera | La Calera | 13 | 7 | 2 | 4 | 14:13 | 1 | 23 |
| 7 | | Everton | Everton | 13 | 6 | 4 | 3 | 12:10 | 2 | 22 |
| 8 | | Antofagasta | Antofagasta | 13 | 7 | 1 | 5 | 17:16 | 1 | 22 |
| 9 | | La Serena | La Serena | 13 | 6 | 3 | 4 | 19:16 | 3 | 21 |
| 10 | | Ñublense | Ñublense | 14 | 5 | 5 | 4 | 20:13 | 7 | 20 |
| 11 | | Palestino | Palestino | 13 | 5 | 4 | 4 | 22:19 | 3 | 19 |
| 12 | | O'Higgins | O'Higgins | 13 | 5 | 4 | 4 | 14:15 | -1 | 19 |
| 13 | | Curicó Unido | Curicó Unido | 13 | 4 | 6 | 3 | 18:16 | 2 | 18 |
| 14 | | Deportes Melipilla | Dep. Melipilla | 14 | 3 | 7 | 4 | 20:20 | 0 | 16 |
| 15 | | Universidad de Chile | Uni. de Chile | 13 | 4 | 4 | 5 | 13:15 | -2 | 16 |
| 16 | | Huachipato | Huachipato | 13 | 2 | 7 | 4 | 10:14 | -4 | 13 |
| 17 | | Santiago Wanderers | Wanderers | 13 | 3 | 2 | 8 | 12:24 | -12 | 11 |
- Copa Libertadores
- Clasificación
- Copa Sudamericana
- Relegation
- Descenso
| # | Team | Team | Pun. | V | E | D | Goles | DG | P. | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | | Colo-Colo | Colo-Colo | 13 | 10 | 2 | 1 | 29:14 | 15 | 32 |
| 2 | | Audax Italiano | Audax Italiano | 14 | 5 | 7 | 2 | 15:11 | 4 | 22 |
| 3 | | Unión La Calera | La Calera | 13 | 6 | 4 | 3 | 18:15 | 3 | 22 |
| 4 | | Universidad de Chile | Uni. de Chile | 13 | 5 | 3 | 5 | 17:16 | 1 | 18 |
| 5 | | Unión Española | Unión Española | 13 | 5 | 1 | 7 | 17:18 | -1 | 16 |
| 6 | | Antofagasta | Antofagasta | 13 | 3 | 7 | 3 | 14:15 | -1 | 16 |
| 7 | | Everton | Everton | 13 | 4 | 4 | 5 | 11:12 | -1 | 16 |
| 8 | | Universidad Católica | U. Católica | 13 | 5 | 0 | 8 | 18:21 | -3 | 15 |
| 9 | | Ñublense | Ñublense | 13 | 3 | 5 | 5 | 16:19 | -3 | 14 |
| 10 | | Palestino | Palestino | 13 | 4 | 2 | 7 | 17:21 | -4 | 14 |
| 11 | | O'Higgins | O'Higgins | 14 | 3 | 4 | 7 | 13:22 | -9 | 13 |
| 12 | | Deportes Melipilla | Dep. Melipilla | 13 | 4 | 1 | 8 | 12:24 | -12 | 13 |
| 13 | | La Serena | La Serena | 14 | 2 | 6 | 6 | 17:21 | -4 | 12 |
| 14 | | Cobresal | CD Cobresal | 13 | 3 | 3 | 7 | 11:17 | -6 | 12 |
| 15 | | Huachipato | Huachipato | 13 | 2 | 5 | 6 | 16:22 | -6 | 11 |
| 16 | | Curicó Unido | Curicó Unido | 13 | 2 | 4 | 7 | 12:18 | -6 | 10 |
| 17 | | Santiago Wanderers | Wanderers | 13 | 2 | 1 | 10 | 9:19 | -10 | 7 |
- Copa Libertadores
- Clasificación
- Copa Sudamericana
- Relegation
- Descenso