Plan de juego
| Fecha | Ronda | Partido | Partido | Res. | Espectadores | |
|---|---|---|---|---|---|---|
| 23.01.2010 |  | 1. Jornada | River Plate - Fénix | Riv - Fén | 0:1 | |
| 31.01.2010 | | 2. Jornada | River Plate - Español | Riv - Esp | 3:3 | |
| 24.02.2010 | | 4. Jornada | River Plate - Danubio | Riv - Dan | 3:0 | |
| 24.03.2010 | | 8. Jornada | River Plate - CA Cerro | Riv - CA | 0:1 | |
| 28.03.2010 | | 10. Jornada | River Plate - Cerrito | Riv - Cer | 3:0 | |
| 04.04.2010 | | 11. Jornada | River Plate - Tacuarembó | Riv - TFC | 3:1 | |
| 25.04.2010 | | 14. Jornada | River Plate - Racing | Riv - Rac | 4:1 | |
| 25.08.2010 | | 1. Jornada | River Plate - Defensor | Riv - Def | 1:1 | |
| 05.09.2010 | | 3. Jornada | River Plate - Español | Riv - Esp | 1:3 | |
| 25.09.2010 | | 5. Jornada | River Plate - Tacuarembó | Riv - TFC | 2:0 | |
| 24.10.2010 | | 9. Jornada | River Plate - Liverpool FC | Riv - LFC | 1:2 | |
| 14.11.2010 | | 12. Jornada | River Plate - El Tanque | Riv - Tan | 1:2 | |
| 27.11.2010 | | 14. Jornada | River Plate - Fénix | Riv - Fén | 1:2 |