Entradas
| a partir de | Apellido | Pos | Equipo | Equipo | ||
|---|---|---|---|---|---|---|
| 12/2022 |  | Andy Cabrera | M |  | Butler Bulldogs | Butler Bulldogs |
| 12/2022 | | Zach Thornton | EP |  | Houston Dynamo | H. Dynamo |
| 11/2022 |  | Andrés Calleja Blanco | Fis | |||
| 05/2022 | | Mihajlo Mišković | P | |||
| 05/2022 | | Chris Mueller | A |  | Hibernian FC | Hibernian FC |
| 05/2022 |  | Ían Torres | M |  | Atlas Guadalajara | Atlas |
| 02/2022 |  | Xherdan Shaqiri | M |  | Olympique Lyonnais | Olympique Lyon |
| 01/2022 |  | Kacper Przybyłko | A |  | Philadelphia Union 2 | Phil. Union 2 |
| 01/2022 | | Kendall Burks | D |  | Washington Huskies | Washington Huskies |
| 01/2022 |  | Yanis Leerman | D |  | Chicago Fire (Preseason) | Chicago Fire (Preseason) |
| 01/2022 | | Charlie Ostrem | D | | Chicago Fire (Preseason) | Chicago Fire (Preseason) |
| 01/2022 | | Carlo Ritaccio | D | | Chicago Fire (Preseason) | Chicago Fire (Preseason) |
| 01/2022 |  | Rafael Czichos | D |  | 1. FC Colonia | 1. FC Colonia |
| 01/2022 | | Andre Reynolds | D |  | Memphis 901 | Memphis 901 |
| 01/2022 | | Sergio Oregel | M |  | Chicago Fire 2 | Chicago Fire 2 |
| 01/2022 |  | Jhon Durán | A |  | Envigado FC | Envigado |
| 01/2022 | | Missael Rodriguez | A |  | Chicago Fire Academy | Chicago Fire Academy |
| 01/2022 |  | Ezra Hendrickson | DT |  | Columbus Crew | Columbus Crew |
| 01/2022 | | Hillary Bell | Fis | |||
| 01/2022 | | Rubén Castro | E-FI |
Salidas
| a partir de | Apellido | Pos | Equipo | Equipo | ||
|---|---|---|---|---|---|---|
| 08/2022 |  | Chinonso Offor | A |  | CF Montréal | Montréal |
| 02/2022 |  | Johan Kappelhof | D |  | Real Salt Lake | Salt Lake |
| 01/2022 |  | Francisco Calvo | D |  | San Jose Earthquakes | Earthquakes |
| 01/2022 |  | Luka Stojanović | M |  | Al Hazem | Al Hazem |
| 01/2022 | | Bobby Shuttleworth | P |  | Atlanta United FC | Atlanta United |
| 01/2022 |  | Elliot Collier | M |  | San Antonio FC | San Antonio FC |
| 01/2022 | | Chris Brady | P | | Chicago Fire (Preseason) | Chicago Fire (Preseason) |
| 01/2022 | | Gabriel Słonina | P | | Chicago Fire (Preseason) | Chicago Fire (Preseason) |
| 01/2022 | | Medrán | M |  | Al Taawoun | Al Taawoun |
| 01/2022 |  | Ignacio Aliseda | A |  | FC Lugano | FC Lugano |