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|
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| 02.04.2022 | 13:45 | Olympiakos Piraeus II | - | Pierikos Katerini | 3:0 (1:0) | |
| 13:45 | PAOK Saloniki II | - | Almopos Arideas | 0:1 (0:1) | ||
| 13:45 | Olympiacos Volou | - | Niki Volou FC | 1:2 (0:2) | ||
| 03.04.2022 | 13:45 | AEP Iraklis FC | - | Apollon Pontou | 0:3 (0:2) | |
| 13:45 | Panserraikos | - | Anagennisi Karditsa | 2:1 (0:1) | ||
| 13:45 | Apollon Lárissa | - | Xanthi FC | 0:0 (0:0) | ||
| 13:45 | AO Trikala | - | AO Kavala | 0:2 (0:0) | ||
| 16:00 | AE Lárissa | - | Thesprotos | 1:0 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Veria FC | 26 | 20 | 4 | 2 | 53:19 | 34 | 64 |
| 2 |
|
AE Lárissa | 26 | 16 | 8 | 2 | 35:11 | 24 | 56 |
| 3 |
|
Xanthi FC | 26 | 11 | 11 | 4 | 36:16 | 20 | 44 |
| 4 |
|
Niki Volou FC | 26 | 12 | 8 | 6 | 32:16 | 16 | 44 |
| 5 |
|
Anagennisi Karditsa | 27 | 13 | 5 | 9 | 39:26 | 13 | 44 |
| 6 |
|
Olympiakos Piraeus II | 26 | 10 | 8 | 8 | 29:26 | 3 | 38 |
| 7 |
|
Almopos Arideas | 26 | 9 | 8 | 9 | 33:26 | 7 | 35 |
| 8 |
|
PAOK Saloniki II | 27 | 8 | 11 | 8 | 29:27 | 2 | 35 |
| 9 |
|
AEP Iraklis FC | 26 | 7 | 13 | 6 | 28:23 | 5 | 34 |
| 10 |
|
Apollon Pontou | 27 | 8 | 8 | 11 | 31:34 | -3 | 32 |
| 11 |
|
Thesprotos | 26 | 7 | 8 | 11 | 29:29 | 0 | 29 |
| 12 |
|
Pierikos Katerini | 27 | 6 | 9 | 12 | 29:40 | -11 | 27 |
| 13 |
|
Apollon Lárissa | 26 | 6 | 9 | 11 | 20:35 | -15 | 27 |
| 14 |
|
AO Kavala | 26 | 6 | 8 | 12 | 22:65 | -43 | 26 |
| 15 |
|
Panserraikos | 26 | 5 | 9 | 12 | 27:35 | -8 | 24 |
| 16 |
|
Olympiacos Volou | 27 | 5 | 7 | 15 | 27:43 | -16 | 22 |
| 17 |
|
AO Trikala | 27 | 5 | 6 | 16 | 17:45 | -28 | 21 |
| Playoff | |
| Descenso |
