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| 07.12.2018 | 20:00 | Sparta Rotterdam | - | Almere City FC | 6:1 (2:1) | |
| 20:00 | FC Volendam | - | FC Twente | 1:2 (0:1) | ||
| 20:00 | RKC Waalwijk | - | MVV | 3:1 (1:0) | ||
| 20:00 | FC Eindhoven | - | FC Utrecht (J) | 0:0 (0:0) | ||
| 20:00 | Go Ahead Eagles | - | Helmond Sport | 1:0 (1:0) | ||
| 20:00 | FC Den Bosch | - | NEC Nijmegen | 3:2 (1:1) | ||
| 20:00 | Roda JC Kerkrade | - | FC Dordrecht | 2:2 (2:0) | ||
| 20:00 | Jong Ajax | - | TOP Oss | 1:0 (1:0) | ||
| 10.12.2018 | 20:00 | Jong PSV | - | SC Cambuur | 1:2 (1:1) | |
| 20:00 | AZ Alkmaar (J) | - | Telstar | 0:2 (0:1) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Den Bosch | 17 | 11 | 3 | 3 | 31:19 | 12 | 36 |
| 2 |
|
Sparta Rotterdam | 17 | 10 | 5 | 2 | 33:16 | 17 | 35 |
| 3 |
|
Go Ahead Eagles | 17 | 11 | 2 | 4 | 31:18 | 13 | 35 |
| 4 |
|
FC Twente | 17 | 10 | 2 | 5 | 33:22 | 11 | 32 |
| 5 |
|
TOP Oss | 17 | 9 | 3 | 5 | 24:16 | 8 | 30 |
| 6 |
|
Roda JC Kerkrade | 17 | 8 | 4 | 5 | 28:21 | 7 | 28 |
| 7 |
|
Almere City FC | 17 | 8 | 4 | 5 | 27:25 | 2 | 28 |
| 8 |
|
Jong PSV | 17 | 7 | 5 | 5 | 35:30 | 5 | 26 |
| 9 |
|
Jong Ajax | 17 | 8 | 1 | 8 | 32:25 | 7 | 25 |
| 10 |
|
NEC Nijmegen | 17 | 7 | 4 | 6 | 31:30 | 1 | 25 |
| 11 |
|
SC Cambuur | 17 | 7 | 4 | 6 | 23:23 | 0 | 25 |
| 12 |
|
MVV | 17 | 6 | 5 | 6 | 18:22 | -4 | 23 |
| 13 |
|
Telstar | 17 | 7 | 1 | 9 | 20:28 | -8 | 22 |
| 14 |
|
FC Volendam | 17 | 5 | 6 | 6 | 21:26 | -5 | 21 |
| 15 |
|
RKC Waalwijk | 17 | 6 | 2 | 9 | 21:26 | -5 | 20 |
| 16 |
|
FC Eindhoven | 17 | 5 | 4 | 8 | 18:20 | -2 | 19 |
| 17 |
|
FC Dordrecht | 17 | 2 | 5 | 10 | 19:32 | -13 | 11 |
| 18 |
|
FC Utrecht (J) | 17 | 2 | 5 | 10 | 19:39 | -20 | 11 |
| 19 |
|
AZ Alkmaar (J) | 17 | 1 | 7 | 9 | 21:34 | -13 | 10 |
| 20 |
|
Helmond Sport | 17 | 1 | 6 | 10 | 17:30 | -13 | 9 |
| Ascenso | |
| Playoff | |
| Playoff |
