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| 10.04.2009 | 20:00 | HFC Haarlem | - | Fortuna Sittard | 2:0 (1:0) | |
| 20:00 | FC Omniworld | - | AGOVV | 0:3 (0:2) | ||
| 20:00 | SC Cambuur | - | Helmond Sport | 2:0 (1:0) | ||
| 20:00 | RKC Waalwijk | - | Telstar | 3:0 (0:0) | ||
| 20:00 | BV Veendam | - | FC Dordrecht | 0:4 (0:3) | ||
| 20:00 | FC Zwolle | - | TOP Oss | 0:0 (0:0) | ||
| 20:00 | FC Eindhoven | - | Go Ahead Eagles | 1:1 (1:0) | ||
| 20:00 | SBV Excelsior | - | FC Emmen | 0:2 (0:0) | ||
| 20:00 | MVV | - | RBC Roosendaal | 4:1 (1:1) | ||
| 20:00 | FC Den Bosch | - | VVV-Venlo | 0:5 (0:1) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
VVV-Venlo | 34 | 22 | 5 | 7 | 76:35 | 41 | 71 |
| 2 |
|
RKC Waalwijk | 34 | 16 | 17 | 1 | 58:26 | 32 | 65 |
| 3 |
|
SC Cambuur | 34 | 17 | 9 | 8 | 61:46 | 15 | 60 |
| 4 |
|
FC Zwolle | 34 | 16 | 8 | 10 | 53:44 | 9 | 56 |
| 5 |
|
MVV | 34 | 14 | 12 | 8 | 52:35 | 17 | 54 |
| 6 |
|
SBV Excelsior | 34 | 14 | 12 | 8 | 49:36 | 13 | 54 |
| 7 |
|
HFC Haarlem | 34 | 15 | 5 | 14 | 40:49 | -9 | 50 |
| 8 |
|
FC Den Bosch | 34 | 13 | 8 | 13 | 56:46 | 10 | 47 |
| 9 |
|
Go Ahead Eagles | 34 | 11 | 14 | 9 | 35:36 | -1 | 47 |
| 10 |
|
Helmond Sport | 34 | 12 | 10 | 12 | 45:46 | -1 | 46 |
| 11 |
|
AGOVV | 34 | 13 | 6 | 15 | 54:62 | -8 | 45 |
| 12 |
|
FC Dordrecht | 34 | 11 | 10 | 13 | 43:36 | 7 | 43 |
| 13 |
|
TOP Oss | 34 | 11 | 8 | 15 | 48:57 | -9 | 41 |
| 14 |
|
FC Emmen | 34 | 11 | 8 | 15 | 45:62 | -17 | 41 |
| 15 |
|
RBC Roosendaal | 34 | 11 | 7 | 16 | 41:47 | -6 | 40 |
| 16 |
|
Telstar | 34 | 9 | 11 | 14 | 40:51 | -11 | 38 |
| 17 |
|
Fortuna Sittard | 34 | 9 | 8 | 17 | 35:53 | -18 | 35 |
| 18 |
|
BV Veendam | 34 | 9 | 9 | 16 | 42:61 | -19 | 33 |
| 19 |
|
FC Eindhoven | 34 | 6 | 14 | 14 | 52:75 | -23 | 29 |
| 20 |
|
FC Omniworld | 34 | 7 | 5 | 22 | 36:58 | -22 | 26 |
| Ascenso | |
| Playoff | |
| Playoff | |
| Playoff | |
| Playoff |
